Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1105
Gene Symbol: CHD1
CHD1 		0.300 Biomarker phenotype CTD_human Role for Chromatin Remodeling Factor Chd1 in Learning and Memory. 30728766 2019
Entrez Id: 50632
Gene Symbol: CALY
CALY 		0.300 Biomarker phenotype CTD_human Increased arterial pressure in mice with overexpression of the ADHD candidate gene calcyon in forebrain. 30753204 2019
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker phenotype CTD_human Importance of tau in cognitive decline as revealed by developmental exposure to lead. 29203278 2018
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Virgin coconut oil (VCO) by normalizing NLRP3 inflammasome showed potential neuroprotective effects in Amyloid-β induced toxicity and high-fat diet fed rat. 29729307 2018
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker phenotype CTD_human Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy. 29860433 2018
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.300 Biomarker phenotype CTD_human Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease. 28448946 2017
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease. 28448946 2017
Entrez Id: 1312
Gene Symbol: COMT
COMT 		0.300 Biomarker phenotype CTD_human Generation of membrane-bound catechol-O-methyl transferase deficient mice with disctinct sex dependent behavioral phenotype. 28195063 2016
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human [Gly14]-Humanin Protects Against Amyloid β Peptide-Induced Impairment of Spatial Learning and Memory in Rats. 27306655 2016
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Lactational exposure of mice to low levels of non-dioxin-like polychlorinated biphenyls increases susceptibility to neuronal stress at a mature age. 26480858 2016
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2 		0.300 Biomarker phenotype CTD_human S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model. 25653350 2015
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Ethosuximide Induces Hippocampal Neurogenesis and Reverses Cognitive Deficits in an Amyloid-β Toxin-induced Alzheimer Rat Model via the Phosphatidylinositol 3-Kinase (PI3K)/Akt/Wnt/β-Catenin Pathway. 26420483 2015
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Selective activation of α7 nicotinic acetylcholine receptor by PHA-543613 improves Aβ25-35-mediated cognitive deficits in mice. 25881725 2015
Entrez Id: 56848
Gene Symbol: SPHK2
SPHK2 		0.300 Biomarker phenotype CTD_human Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory. 24859201 2014
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.300 Biomarker phenotype CTD_human Notoginsenoside R1 increases neuronal excitability and ameliorates synaptic and memory dysfunction following amyloid elevation. 25213453 2014
Entrez Id: 9365
Gene Symbol: KL
KL 		0.300 Biomarker phenotype CTD_human Growth Hormone-Releaser Diet Attenuates Cognitive Dysfunction in Klotho Mutant Mice via Insulin-Like Growth Factor-1 Receptor Activation in a Genetic Aging Model. 25309793 2014
Entrez Id: 9365
Gene Symbol: KL
KL 		0.300 Biomarker phenotype CTD_human Melatonin attenuates memory impairment induced by Klotho gene deficiency via interactive signaling between MT2 receptor, ERK, and Nrf2-related antioxidant potential. 25550330 2014
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Potassium 2-(1-hydroxypentyl)-benzoate promotes long-term potentiation in Aβ1-42-injected rats and APP/PS1 transgenic mice. 24858312 2014
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker phenotype CTD_human Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity. 24556215 2014
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Notoginsenoside R1 increases neuronal excitability and ameliorates synaptic and memory dysfunction following amyloid elevation. 25213453 2014
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptoms. 23827522 2013
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Protective effects of astragalosides on dexamethasone and Aβ25-35 induced learning and memory impairments due to decrease amyloid precursor protein expression in 12-month male rats. 22484447 2012
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker phenotype CTD_human A proteomic analysis of MCLR-induced neurotoxicity: implications for Alzheimer's disease. 22430071 2012
Entrez Id: 6855
Gene Symbol: SYP
SYP 		0.300 Biomarker phenotype CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146 2011
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker phenotype CTD_human A dopamine receptor (DRD2) but not dopamine transporter (DAT1) gene polymorphism is associated with neurocognitive development of Mexican preschool children with lead exposure. 21592505 2011