×
Entrez Id: 6832
Gene Symbol: SUPV3L1
SUPV3L1
0.310
Biomarker
phenotype
CTD_human
Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death.
19145458 2009
×
Entrez Id: 6832
Gene Symbol: SUPV3L1
SUPV3L1
0.310
Biomarker
phenotype
BEFREE
Disruption of Supv3L1 damages the skin and causes sarcopenia , loss of fat, and death.
19145458 2009
×
Entrez Id: 367
Gene Symbol: AR
AR
0.210
Therapeutic
phenotype
RGD
A selective androgen receptor modulator that reduces prostate tumor size and prevents orchidectomy-induced bone loss in rats.
17049844 2007
×
Entrez Id: 367
Gene Symbol: AR
AR
0.210
Biomarker
phenotype
BEFREE
Prevention of body weight loss and sarcopenia by a novel selective androgen receptor modulator in cancer cachexia models.
29344250 2017
×
Entrez Id: 4303
Gene Symbol: FOXO4
FOXO4
0.210
Biomarker
phenotype
BEFREE
The WNK1-FOXO4 axis may be a potential therapeutic target in human diseases causing sarcopenia .
29904119 2018
×
Entrez Id: 4303
Gene Symbol: FOXO4
FOXO4
0.210
Biomarker
phenotype
RGD
Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle.
16870627 2006
PPARGC1A
0.200
Biomarker
phenotype
RGD
No decline in skeletal muscle oxidative capacity with aging in long-term calorically restricted rats: effects are independent of mitochondrial DNA integrity.
16870628 2006
×
Entrez Id: 51024
Gene Symbol: FIS1
FIS1
0.200
Biomarker
phenotype
RGD
Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle.
23220115 2013
×
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
0.200
Biomarker
phenotype
RGD
Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle.
23220115 2013
×
Entrez Id: 498
Gene Symbol: ATP5F1A
ATP5F1A
0.200
Biomarker
phenotype
RGD
Proteomic study of calpain interacting proteins during skeletal muscle aging.
20850499 2010
×
Entrez Id: 9927
Gene Symbol: MFN2
MFN2
0.200
Biomarker
phenotype
RGD
Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle.
23220115 2013
×
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.200
Biomarker
phenotype
RGD
Elevated caspase and AIF gene expression correlate with progression of sarcopenia during aging in male F344BN rats.
17029665 2006
×
Entrez Id: 203
Gene Symbol: AK1
AK1
0.200
Biomarker
phenotype
RGD
Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle.
17611631 2007
×
Entrez Id: 1965
Gene Symbol: EIF2S1
EIF2S1
0.200
Biomarker
phenotype
RGD
Assessment of biomarkers of protein anabolism in skeletal muscle during the life span of the rat: sarcopenia despite elevated protein synthesis.
15187001 2004
×
Entrez Id: 8893
Gene Symbol: EIF2B5
EIF2B5
0.200
Biomarker
phenotype
RGD
Assessment of biomarkers of protein anabolism in skeletal muscle during the life span of the rat: sarcopenia despite elevated protein synthesis.
15187001 2004
×
Entrez Id: 581
Gene Symbol: BAX
BAX
0.200
Biomarker
phenotype
RGD
Elevated caspase and AIF gene expression correlate with progression of sarcopenia during aging in male F344BN rats.
17029665 2006
×
Entrez Id: 9131
Gene Symbol: AIFM1
AIFM1
0.200
ModifyingMutation
phenotype
RGD
Elevated caspase and AIF gene expression correlate with progression of sarcopenia during aging in male F344BN rats.
17029665 2006
×
Entrez Id: 4792
Gene Symbol: NFKBIA
NFKBIA
0.200
Biomarker
phenotype
RGD
Muscle fiber specific apoptosis and TNF-alpha signaling in sarcopenia are attenuated by life-long calorie restriction.
15665035 2005
×
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100
AlteredExpression
phenotype
BEFREE
Body composition metrics such as sarcopenia and low psoas muscle density in addition to low albumin level were able to stratify patients into different prognostic categories.
29855867 2018
×
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.100
GeneticVariation
phenotype
BEFREE
To investigate the effects of resistance training and epicatechin supplementation on muscle strength, follistatin, and myostatin in older adults with sarcopenia , a total of 62 males with sarcopenia (68.63 ± 2.86 years) underwent a supervised 8-week randomized controlled trial.
30299198 2019
×
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.100
Biomarker
phenotype
BEFREE
Novel strategies to reverse sarcopenia such as hormone supplementation, long-term ammonia-lowering agents and myostatin antagonists, are currently under investigation.
31701570 2020
×
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100
Biomarker
phenotype
BEFREE
Sarcopenia was present in 69 of 240 patients (28.8%) and was associated with lower body mass index, lower serum albumin , lower hemoglobin, and higher nutritional risk screening 2002 scores.28501109 2017
×
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100
AlteredExpression
phenotype
BEFREE
Sarcopenia was significantly associated with urinary albumin level with a pooled OR of 2.11 (95% CI, 1.55-2.88; <i>P</i> < 0.001).31828155 2019
×
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100
Biomarker
phenotype
BEFREE
Slow gait speed was present in 95 out of 357 patients (26.61%) which was significantly associated with age (P < 0.001), gender (P = 0.016), plasma albumin (P < 0.001), American Society of Anesthesiologists grade (P = 0.012), tumour-node-metastasis grade (P = 0.007), sarcopenia (P < 0.001), handgrip (P < 0.001) and post-operative medical complications (P = 0.022).
29228514 2019
×
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100
Biomarker
phenotype
BEFREE
102 women met inclusion criteria.Sarcopenia correlated with albumin (P = 0.0002).
29409111 2018