Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6832
Gene Symbol: SUPV3L1
SUPV3L1
0.310 Biomarker phenotype CTD_human Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death. 19145458 2009
Entrez Id: 6832
Gene Symbol: SUPV3L1
SUPV3L1
0.310 Biomarker phenotype BEFREE Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death. 19145458 2009
Entrez Id: 4303
Gene Symbol: FOXO4
FOXO4
0.210 Biomarker phenotype BEFREE The WNK1-FOXO4 axis may be a potential therapeutic target in human diseases causing sarcopenia. 29904119 2018
Entrez Id: 367
Gene Symbol: AR
AR
0.210 Biomarker phenotype BEFREE Prevention of body weight loss and sarcopenia by a novel selective androgen receptor modulator in cancer cachexia models. 29344250 2017
Entrez Id: 367
Gene Symbol: AR
AR
0.210 Therapeutic phenotype RGD A selective androgen receptor modulator that reduces prostate tumor size and prevents orchidectomy-induced bone loss in rats. 17049844 2007
Entrez Id: 4303
Gene Symbol: FOXO4
FOXO4
0.210 Biomarker phenotype RGD Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle. 16870627 2006
Entrez Id: 51024
Gene Symbol: FIS1
FIS1
0.200 Biomarker phenotype RGD Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle. 23220115 2013
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
0.200 Biomarker phenotype RGD Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle. 23220115 2013
Entrez Id: 9927
Gene Symbol: MFN2
MFN2
0.200 Biomarker phenotype RGD Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle. 23220115 2013
Entrez Id: 498
Gene Symbol: ATP5F1A
ATP5F1A
0.200 Biomarker phenotype RGD Proteomic study of calpain interacting proteins during skeletal muscle aging. 20850499 2010
Entrez Id: 203
Gene Symbol: AK1
AK1
0.200 Biomarker phenotype RGD Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle. 17611631 2007
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
0.200 Biomarker phenotype RGD No decline in skeletal muscle oxidative capacity with aging in long-term calorically restricted rats: effects are independent of mitochondrial DNA integrity. 16870628 2006
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.200 Biomarker phenotype RGD Elevated caspase and AIF gene expression correlate with progression of sarcopenia during aging in male F344BN rats. 17029665 2006
Entrez Id: 581
Gene Symbol: BAX
BAX
0.200 Biomarker phenotype RGD Elevated caspase and AIF gene expression correlate with progression of sarcopenia during aging in male F344BN rats. 17029665 2006
Entrez Id: 9131
Gene Symbol: AIFM1
AIFM1
0.200 ModifyingMutation phenotype RGD Elevated caspase and AIF gene expression correlate with progression of sarcopenia during aging in male F344BN rats. 17029665 2006
Entrez Id: 4792
Gene Symbol: NFKBIA
NFKBIA
0.200 Biomarker phenotype RGD Muscle fiber specific apoptosis and TNF-alpha signaling in sarcopenia are attenuated by life-long calorie restriction. 15665035 2005
Entrez Id: 1965
Gene Symbol: EIF2S1
EIF2S1
0.200 Biomarker phenotype RGD Assessment of biomarkers of protein anabolism in skeletal muscle during the life span of the rat: sarcopenia despite elevated protein synthesis. 15187001 2004
Entrez Id: 8893
Gene Symbol: EIF2B5
EIF2B5
0.200 Biomarker phenotype RGD Assessment of biomarkers of protein anabolism in skeletal muscle during the life span of the rat: sarcopenia despite elevated protein synthesis. 15187001 2004
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.100 Biomarker phenotype BEFREE Novel strategies to reverse sarcopenia such as hormone supplementation, long-term ammonia-lowering agents and myostatin antagonists, are currently under investigation. 31701570 2020
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker phenotype BEFREE Circulating albumin and cholinesterase have the potential to predicting sarcopenia as biomarkers. 31102055 2020
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.100 Biomarker phenotype BEFREE In this study, we investigated the effect of low-magnitude high-frequency vibration (LMHFV) on osteoporotic fracture with sarcopenia and the potential role of myostatin. 31535727 2020
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker phenotype BEFREE Sarcopenia and albumin (P = 0.045, 0.023; hazard ratio (HR), 2.309, 2.652; 95% CI 1.021-5.225, 1.141-6.165, respectively) were independent predictors of OS in multivariate analysis. 31520176 2020
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker phenotype BEFREE Age, BMI, diabetes, hypertension, fasting glucose, aspartate aminotransferase, and liver stiffness value were correlated positively with sarcopenia (all P < 0.05), whereas male sex, viral etiology, obesity (BMI > 25 kg/m), total bilirubin, and serum albumin were correlated negatively with sarcopenia (all P < 0.05). 31283527 2020
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.100 GeneticVariation phenotype BEFREE To investigate the effects of resistance training and epicatechin supplementation on muscle strength, follistatin, and myostatin in older adults with sarcopenia, a total of 62 males with sarcopenia (68.63 ± 2.86 years) underwent a supervised 8-week randomized controlled trial. 30299198 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 AlteredExpression phenotype BEFREE Sarcopenia was significantly associated with urinary albumin level with a pooled OR of 2.11 (95% CI, 1.55-2.88; <i>P</i> < 0.001). 31828155 2019