Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.020 Biomarker disease BEFREE The patient was transferred to Critical Care Unit for monitoring; 100 mg of alteplase was initiated immediately and alleviated the hemodynamic instability within 2 hours of intravenous administration. 29642185 2018
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.020 Biomarker disease BEFREE Administration of low-dosage alteplase in primigravida with hemodynamic instability is extremely rare and controversial; however, our case suggests that this treatment strategy is relatively safe and feasible. 30412129 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.010 GeneticVariation disease BEFREE Participants responded that new onset of hemodynamic instability and rising C-reactive protein (49%) or rising procalcitonin (30%) are the most common triggers to commence antibiotics. 31136375 2019
Entrez Id: 65065
Gene Symbol: NBEAL1
NBEAL1
0.010 Biomarker disease BEFREE Hemodynamic instability frequently occurs in beach chair positioning for surgery, putting patients at risk for cerebral adverse events. 30322751 2018
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.010 GeneticVariation disease BEFREE REBOA indication relied on (1) extreme hemodynamic instability (systolic arterial blood pressure [SBP] < 60 mm Hg on admission, SBP < 90 mm Hg despite initial resuscitation in the trauma bay or posttraumatic cardiac arrest) and (2) positive pelvic X-ray. 29298239 2018
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.010 Biomarker disease BEFREE On multivariable analysis, adrenal response to the ACTH test was a significant independent predictor of hemodynamic instability at 48 hours after surgery (odds ratio 1.06 [95% confidence interval: 1.02 to 1.11] per 10 nmol/L cortisol decrease; p = 0.002). 29750931 2018
Entrez Id: 6462
Gene Symbol: SHBG
SHBG
0.010 GeneticVariation disease BEFREE REBOA indication relied on (1) extreme hemodynamic instability (systolic arterial blood pressure [SBP] < 60 mm Hg on admission, SBP < 90 mm Hg despite initial resuscitation in the trauma bay or posttraumatic cardiac arrest) and (2) positive pelvic X-ray. 29298239 2018
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
0.010 GeneticVariation disease BEFREE REBOA indication relied on (1) extreme hemodynamic instability (systolic arterial blood pressure [SBP] < 60 mm Hg on admission, SBP < 90 mm Hg despite initial resuscitation in the trauma bay or posttraumatic cardiac arrest) and (2) positive pelvic X-ray. 29298239 2018
Entrez Id: 2056
Gene Symbol: EPO
EPO
0.010 Biomarker disease BEFREE Postoperative erythropoietin administration was not effective in preventing blood transfusion for anemia or parenteral hydration for hemodynamic instability in patients undergoing major liposuction. 28039503 2017
Entrez Id: 133
Gene Symbol: ADM
ADM
0.010 Biomarker disease BEFREE Adrenomedullin is a prognostic biomarker in several cardiovascular diseases and was recently shown to associate with hemodynamic instability in patients with septic shock. 28050899 2017
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.010 Biomarker disease BEFREE Traditional risk factors including increased ASA physical status score, emergent surgery, intraoperative blood loss and hemodynamic instability are consistently associated with increased mortality using most scoring systems. 28820798 2017
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.010 AlteredExpression disease BEFREE Increasing cell doses were associated with high serum levels of IL12 and IFNγ as well as clinical toxicities, including liver dysfunction, high fevers, and sporadic life-threatening hemodynamic instability. 25695689 2015
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
0.010 AlteredExpression disease BEFREE Mice lacking GR showed significantly increased mortality, more hemodynamic instability, higher nitric oxide levels, and higher levels of the inflammatory cytokines, tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) compared with controls. 23248291 2013
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.010 AlteredExpression disease BEFREE Mice lacking GR showed significantly increased mortality, more hemodynamic instability, higher nitric oxide levels, and higher levels of the inflammatory cytokines, tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) compared with controls. 23248291 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.010 AlteredExpression disease BEFREE Mice lacking GR showed significantly increased mortality, more hemodynamic instability, higher nitric oxide levels, and higher levels of the inflammatory cytokines, tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) compared with controls. 23248291 2013
Entrez Id: 100128998
Gene Symbol: C20orf181
C20orf181
0.010 Biomarker disease BEFREE Several reports have described the successful use of t-PA in the setting of hemodynamic instability in gravidas with massive pulmonary emboli. 16260552 2005