Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 GeneticVariation disease CLINVAR Genetic mutations of p53 and k-ras in gastric carcinoma patients from Hunan, China. 21080251 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study. 21601526 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Pleomorphic carcinoma of the lung arising in a patient with Li-Fraumeni syndrome: report of a case. 21626334 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 GeneticVariation disease CLINVAR Prevalence of germline TP53 mutations in a prospective series of unselected patients with adrenocortical carcinoma. 23175693 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 GeneticVariation disease CLINVAR The genetic landscape of high-risk neuroblastoma. 23334666 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Joint effects of germ-line TP53 mutation, MDM2 SNP309, and gender on cancer risk in family studies of Li-Fraumeni syndrome. 21305319 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Molecular basis of the Li-Fraumeni syndrome: an update from the French LFS families. 18511570 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Germ-line p53 mutations in 15 families with Li-Fraumeni syndrome. 7887414 1995
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Detection of high frequency of mutations in a breast and/or ovarian cancer cohort: implications of embracing a multi-gene panel in molecular diagnosis in India. 26911350 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 GeneticVariation disease CLINVAR Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel. 25186627 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 GeneticVariation disease CLINVAR Malignant peritoneal mesothelioma in a patient with Li-Fraumeni syndrome. 21464421 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis. 23538418 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis. 23161690 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Gastric cancer in individuals with Li-Fraumeni syndrome. 21552135 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Occurrence of Neuroblastoma among TP53 p.R337H Carriers. 26452166 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 GeneticVariation disease CLINVAR BRCA1, TP53, and CHEK2 germline mutations in uterine serous carcinoma. 22811390 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes. 20522432 2010
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Early onset HER2-positive breast cancer is associated with germline TP53 mutations. 21761402 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Research and Clinical Care. 26786923 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes. 21343334 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 GeneticVariation disease CLINVAR Clinical Application of Multigene Panels: Challenges of Next-Generation Counseling and Cancer Risk Management. 26484312 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR R337H mutation of the TP53 gene as a clinical marker in cancer patients: a systematic review of literature. 26681051 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 GeneticVariation disease CLINVAR Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease. 24556621 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 CausalMutation disease CLINVAR Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation. 20128691 2010
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 GeneticVariation disease CLINVAR TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes. 20522432 2010