| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.400 | AlteredExpression | disease | BEFREE | After treatment with E2, NOS III, ER alpha, and ER beta mRNA expression was enhanced in arterial vessels of postmenopausal women with CAD. | 16207548 | 2005 | ||||
|
0.400 | GeneticVariation | disease | LHGDN | This study seeks to investigate the association between the ESR1 haplotype created by the c.454-397 T>C and c.454-351 A>G polymorphisms, the length of the (TA)n repeats, and the angiographic extent of CAD. | 16159931 | 2005 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | Estrogen receptor alpha (ESR1) gene variation is associated with a range of important estrogen-dependent characteristics, including responses of lipid profile and atherosclerotic severity to hormone replacement therapy, coronary heart disease risk, and migraine. | 16179580 | 2005 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | The (TA)(n)length in the ER-alpha gene promoter region is associated with the angiographic severity of CAD in young patients. | 14972425 | 2004 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | Molecular analysis of the estrogen receptor alpha gene in men with coronary artery disease: association with disease status. | 12691862 | 2003 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease. | 11919305 | 2002 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | We conclude that -1989T/G or its linked polymorphisms in the ER-alpha gene may confer risk for CAD and that the G/G genotype may be an independent predictor for CAD in patients with familial hypercholesterolemia. | 12006396 | 2002 | ||||
|
0.400 | Biomarker | disease | CTD_human | Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man. | 9396482 | 1997 |