Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2322
Gene Symbol: FLT3
FLT3 		0.800 Biomarker disease CTD_human
Entrez Id: 2322
Gene Symbol: FLT3
FLT3 		0.800 GeneticVariation disease UNIPROT
Entrez Id: 2322
Gene Symbol: FLT3
FLT3 		0.800 CausalMutation disease CGI
Entrez Id: 2322
Gene Symbol: FLT3
FLT3 		0.800 Biomarker disease HPO
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE IKZF1 deletion and co-occurrence with other aberrations in a child with chronic myeloid leukemia progressing to acute lymphoblastic leukemia. 30511400 2019
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia. 30877974 2019
Entrez Id: 5079
Gene Symbol: PAX5
PAX5 		0.700 Biomarker disease BEFREE PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia. 30643249 2019
Entrez Id: 5079
Gene Symbol: PAX5
PAX5 		0.700 GeneticVariation disease BEFREE PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia. 30842609 2019
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE IKZF1 Gene Deletion in Pediatric Patients Diagnosed with Acute Lymphoblastic Leukemia in Mexico. 30974435 2019
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 Biomarker disease BEFREE An 11-year-old male patient with the deletion of <i>IKZF1</i> (Ikaros family zinc finger 1) and positive Breakpoint Cluster Region-C-Abelson oncogene 1(<i>BCR-ABL1</i>) acute lymphoblastic leukemia developed mucositis, gastrointestinal toxicity, hepatotoxicity, myelosuppression, and severe dermatologic toxicity during the first and second courses of high-dose methotrexate. 31607921 2019
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE IKZF1 genetic variants rs4132601 and rs11978267 and acute lymphoblastic leukemia risk in Tunisian children: a case-control study. 31604453 2019
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 Biomarker disease BEFREE Plant homeodomain finger protein 2 as a novel IKAROS target in acute lymphoblastic leukemia. 28994305 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease GWASCAT GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21. 29348612 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia. 29507076 2018
Entrez Id: 5079
Gene Symbol: PAX5
PAX5 		0.700 GeneticVariation disease BEFREE A novel PAX5 rearrangement in TCF3-PBX1 acute lymphoblastic leukemia: a case report. 30563523 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 Biomarker disease BEFREE By contrast, the MRD15 was higher in Ikaros family Zinc Finger Protein 1 (<i>IKZF1)</i>-deleted BCP-ALL patients than in BCP-ALL patients without <i>IKZF1</i> deletions [1.18% (0.06-12.0%) vs 0.33% (0.03-2.6%); p=0.003]. 29899835 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 Biomarker disease BEFREE The many faces of IKZF1 in B-cell precursor acute lymphoblastic leukemia. 29519871 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 Biomarker disease BEFREE Intensifying Treatment of Childhood B-Lymphoblastic Leukemia With IKZF1 Deletion Reduces Relapse and Improves Overall Survival: Results of Malaysia-Singapore ALL 2010 Study. 30044693 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE Development of a Fluorescence in Situ Hybridization Probe for Detecting IKZF1 Deletion Mutations in Patients with Acute Lymphoblastic Leukemia. 29957452 2018
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 Biomarker disease BEFREE Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome. 28190000 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GeneticVariation disease BEFREE Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients. 27979924 2017
Entrez Id: 5079
Gene Symbol: PAX5
PAX5 		0.700 GeneticVariation disease BEFREE IKZF1 and PAX5 deletions were observed in 13 and 17% of B-LBL, respectively, which was similar to the reported frequency in B-ALL. 27957801 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 AlteredExpression disease BEFREE IKZF1 alterations and expression of CRLF2 predict prognosis in adult Chinese patients with B-cell precursor acute lymphoblastic leukemia. 27157479 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 Biomarker disease BEFREE IKZF1 and PAX5 deletions were observed in 13 and 17% of B-LBL, respectively, which was similar to the reported frequency in B-ALL. 27957801 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 AlteredExpression disease BEFREE Genetic alterations of the transcription factor IKZF1 ("IKAROS") are detected in around 15-30% of cases of <i>BCR-ABL</i>-negative B-cell precursor acute lymphoblastic leukemia. 28751559 2017