Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Identification of a Novel BRCA1 Pathogenic Mutation in Korean Patients Following Reclassification of BRCA1 and BRCA2 Variants According to the ACMG Standards and Guidelines Using Relevant Ethnic Controls. 28111427 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Current guidelines for BRCA testing of breast cancer patients are insufficient to detect all mutation carriers. 28637432 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR BRCA1/2 missense mutations and the value of in-silico analyses. 28807866 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Prevalence of pathogenic germline variants detected by multigene sequencing in unselected Japanese patients with ovarian cancer. 29348823 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 GeneticVariation phenotype CLINVAR Improving performance of multigene panels for genomic analysis of cancer predisposition. 26845104 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results. 28008555 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Prevalence of Hispanic BRCA1 and BRCA2 mutations among hereditary breast and ovarian cancer patients from Brazil reveals differences among Latin American populations. 27425403 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Mutational analysis of BRCA1 and BRCA2 genes in Peruvian families with hereditary breast and ovarian cancer. 28944232 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 GeneticVariation phenotype CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Evaluation of germline BRCA1 and BRCA2 mutations in a multi-ethnic Asian cohort of ovarian cancer patients. 26541979 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Improving performance of multigene panels for genomic analysis of cancer predisposition. 26845104 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR In silico, in vitro and case-control analyses as an effective combination for analyzing BRCA1 and BRCA2 unclassified variants in a population-based sample. 27886673 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Mutation detection rates associated with specific selection criteria for BRCA1/2 testing in 1854 high-risk families: A monocentric Italian study. 27062684 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Detection of Germline Mutation in Hereditary Breast and/or Ovarian Cancers by Next-Generation Sequencing on a Four-Gene Panel. 27157322 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Clinical Next-Generation Sequencing Pipeline Outperforms a Combined Approach Using Sanger Sequencing and Multiplex Ligation-Dependent Probe Amplification in Targeted Gene Panel Analysis. 27376475 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 Biomarker phenotype CLINGEN Frequency of mutations in a large series of clinically ascertained ovarian cancer cases tested on multi-gene panels compared to reference controls. 28888541 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Assessing the spectrum of germline variation in Fanconi anemia genes among patients with head and neck carcinoma before age 50. 28678401 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Characteristics of BRCA1/2 mutations carriers including large genomic rearrangements in high risk breast cancer patients. 28205045 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Identification of germline alterations in breast cancer predisposition genes among Malaysian breast cancer patients using panel testing. 26757417 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer. 27153395 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Functional classification of DNA variants by hybrid minigenes: Identification of 30 spliceogenic variants of BRCA2 exons 17 and 18. 28339459 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 CausalMutation phenotype CLINVAR Detecting splicing patterns in genes involved in hereditary breast and ovarian cancer. 28905878 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.600 GeneticVariation phenotype CLINVAR Adding In Silico Assessment of Potential Splice Aberration to the Integrated Evaluation of BRCA Gene Unclassified Variants. 26913838 2016