×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
Biomarker
disease
GENOMICS_ENGLAND
Mutations in BAG3 cause adult-onset Charcot-Marie-Tooth disease.
28754666
2018
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
Biomarker
disease
GENOMICS_ENGLAND
Whole exome sequencing identified 1 base pair novel deletion in BCL2-associated athanogene 3 (BAG3) gene associated with severe dilated cardiomyopathy (DCM) requiring heart transplant in multiple family members.
28211974
2017
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling.
27321750
2016
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
Exome sequencing identifies variants in two genes encoding the LIM-proteins NRAP and FHL1 in an Italian patient with BAG3 myofibrillar myopathy.
27443559
2016
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
BAG3-related myopathy, polyneuropathy and cardiomyopathy with long QT syndrome.
26545904
2015
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
BAG3 myofibrillar myopathy presenting with cardiomyopathy.
25728519
2015
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
Nonsense mutations in BAG3 are associated with early-onset dilated cardiomyopathy in French Canadians.
25448463
2014
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
The BAG3 gene variants in Polish patients with dilated cardiomyopathy: four novel mutations and a genotype-phenotype correlation.
25008357
2014
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
Unusual multisystemic involvement and a novel BAG3 mutation revealed by NGS screening in a large cohort of myofibrillar myopathies.
25208129
2014
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
Zebrafish models of BAG3 myofibrillar myopathy suggest a toxic gain of function leading to BAG3 insufficiency.
25273835
2014
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
BAG3 mutations: another cause of giant axonal neuropathy.
22734908
2012
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
Biomarker
disease
GENOMICS_ENGLAND
BAG3 mutations: another cause of giant axonal neuropathy.
22734908
2012
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
BAG3-related myofibrillar myopathy in a Chinese family.
21361913
2012
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytes.
21898660
2011
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
GeneticVariation
disease
UNIPROT
Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytes.
21898660
2011
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
Genome-wide studies of copy number variation and exome sequencing identify rare variants in BAG3 as a cause of dilated cardiomyopathy.
21353195
2011
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
GeneticVariation
disease
UNIPROT
Genome-wide studies of copy number variation and exome sequencing identify rare variants in BAG3 as a cause of dilated cardiomyopathy.
21353195
2011
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
GeneticVariation
disease
UNIPROT
A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy.
21459883
2011
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
Inheritance patterns and phenotypic features of myofibrillar myopathy associated with a BAG3 mutation.
20605452
2010
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
Mutation in BAG3 causes severe dominant childhood muscular dystrophy.
19085932
2009
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
CausalMutation
disease
CLINVAR
Activation of multiple signal transduction pathways by endothelin in cultured human vascular smooth muscle cells.
2159883
1990
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
Biomarker
disease
MGD
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
Biomarker
disease
GENOMICS_ENGLAND
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
GeneticVariation
disease
CLINVAR
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
0.900
Biomarker
disease
CTD_human