Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 Biomarker disease MGD New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis. 30898653 2019
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 Biomarker disease GENOMICS_ENGLAND Whole-exome sequencing in the evaluation of fetal structural anomalies: a prospective cohort study. 30712878 2019
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Spectrum of mutations and genotype-phenotype analysis in Noonan syndrome patients with RIT1 mutations. 26714497 2016
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR The lymphatic phenotype in Noonan and Cardiofaciocutaneous syndrome. 26242988 2016
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Two cases of RIT1 associated Noonan syndrome: Further delineation of the clinical phenotype and review of the literature. 27109146 2016
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Mutations in RIT1 cause Noonan syndrome - additional functional evidence and expanding the clinical phenotype. 25959749 2016
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Mutations in RIT1 cause Noonan syndrome with possible juvenile myelomonocytic leukemia but are not involved in acute lymphoblastic leukemia. 26757980 2016
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 GeneticVariation disease UNIPROT Mutations in RIT1 cause Noonan syndrome - additional functional evidence and expanding the clinical phenotype. 25959749 2016
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Genotype and phenotype in patients with Noonan syndrome and a RIT1 mutation. 27101134 2016
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1). 27226556 2016
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Recent advances in RASopathies. 26446362 2016
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 Biomarker disease GENOMICS_ENGLAND Contribution of RIT1 mutations to the pathogenesis of Noonan syndrome: four new cases and further evidence of heterogeneity. 24939608 2014
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR The usefulness of whole-exome sequencing in routine clinical practice. 24901346 2014
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Further evidence of the importance of RIT1 in Noonan syndrome. 25124994 2014
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Next-generation sequencing identifies rare variants associated with Noonan syndrome. 25049390 2014
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Contribution of RIT1 mutations to the pathogenesis of Noonan syndrome: four new cases and further evidence of heterogeneity. 24939608 2014
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Oncogenic RIT1 mutations in lung adenocarcinoma. 24469055 2014
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 Biomarker disease GENOMICS_ENGLAND Gain-of-function mutations in RIT1 cause Noonan syndrome, a RAS/MAPK pathway syndrome. 23791108 2013
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 GeneticVariation disease UNIPROT Gain-of-function mutations in RIT1 cause Noonan syndrome, a RAS/MAPK pathway syndrome. 23791108 2013
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Gain-of-function mutations in RIT1 cause Noonan syndrome, a RAS/MAPK pathway syndrome. 23791108 2013
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR [Bone marrow transplantation: principles, indications and results]. 2657980 1989
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 CausalMutation disease CLINVAR Lichenoid tissue reaction (LTR) induced by local transfer of Ia-reactive T-cell clones. II. LTR by epidermal invasion of cytotoxic lymphokine-producing autoreactive T cells. 2439608 1987
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 GeneticVariation disease CLINVAR
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.900 Biomarker disease CTD_human