Source: ALL
Associated Disease N. genes N. variants N. of shared genes JI g p-value g N. of shared variants JI v p-value v
CUI: C0231687
Disease: Spastic gait
Spastic gait 		62 9 23 0.20 1 2.2E-02
CUI: C0037773
Disease: Spastic Paraplegia, Hereditary
Spastic Paraplegia, Hereditary 		123 41 33 0.20 3 4.0E-02
CUI: C1836296
Disease: Muscle Weakness Lower Limb
Muscle Weakness Lower Limb 		74 15 24 0.19 1 2.0E-02
CUI: C0037772
Disease: Spastic Paraplegia
Spastic Paraplegia 		144 93 33 0.18 3 2.4E-02
CUI: C0034935
Disease: Babinski Reflex
Babinski Reflex 		218 11 41 0.16 1 2.1E-02
CUI: C1271100
Disease: Lower limb spasticity
Lower limb spasticity 		43 5 16 0.16 2 5.0E-02
CUI: C0751603
Disease: Autosomal Recessive Hereditary Spastic Paraplegia
Autosomal Recessive Hereditary Spastic Paraplegia 		20 0 12 0.14 0 0
CUI: C1836696
Disease: Lower limb hyperreflexia
Lower limb hyperreflexia 		38 0 14 0.14 0 0
CUI: C0238651
Disease: Ankle clonus
Ankle clonus 		32 5 13 0.14 1 2.4E-02
CUI: C1843175
Disease: Hyperreflexia in upper limbs
Hyperreflexia in upper limbs 		16 0 11 0.14 0 0
CUI: C1852470
Disease: Extrapyramidal muscular rigidity
Extrapyramidal muscular rigidity 		11 0 10 0.13 0 0
CUI: C0542223
Disease: Loss of speech
Loss of speech 		37 0 13 0.13 0 0
CUI: C1848736
Disease: Distal amyotrophy
Distal amyotrophy 		106 0 20 0.12 0 0
CUI: C1295585
Disease: Decreased vibratory sense
Decreased vibratory sense 		33 0 11 0.11 0 0
CUI: C1843663
Disease: Urinary bladder sphincter dysfunction
Urinary bladder sphincter dysfunction 		28 0 10 0.11 0 0
CUI: C1849156
Disease: Spastic Ataxia
Spastic Ataxia 		28 3 10 0.11 1 2.6E-02
CUI: C0575059
Disease: Spastic tetraparesis
Spastic tetraparesis 		50 0 12 0.11 0 0
CUI: C4022417
Disease: Degeneration of the striatum
Degeneration of the striatum 		9 0 8 0.11 0 0
CUI: C1833434
Disease: Multifocal cerebral white matter abnormalities
Multifocal cerebral white matter abnormalities 		10 0 8 0.10 0 0
CUI: C1845245
Disease: Lower limb hypertonia
Lower limb hypertonia 		21 0 9 0.10 0 0
CUI: C0850703
Disease: Frequent falls
Frequent falls 		94 0 15 9.7E-02 0 0
CUI: C0270922
Disease: Peripheral demyelinating neuropathy
Peripheral demyelinating neuropathy 		95 0 15 9.7E-02 0 0
CUI: C0751602
Disease: Hereditary Autosomal Dominant Spastic Paraplegia
Hereditary Autosomal Dominant Spastic Paraplegia 		27 0 9 9.7E-02 0 0
CUI: C0085606
Disease: Urgency of micturition
Urgency of micturition 		40 0 10 9.5E-02 0 0
CUI: C0039273
Disease: Talipes cavus
Talipes cavus 		213 0 25 9.5E-02 0 0