Source: ALL
Associated Disease N. genes N. variants N. of shared genes JI g p-value g N. of shared variants JI v p-value v
CUI: C0231687
Disease: Spastic gait
Spastic gait 		62 0 16 0.22 0 0
CUI: C4553976
Disease: Urinary Urgency, CTCAE 5
Urinary Urgency, CTCAE 5 		34 0 11 0.22 0 0
CUI: C0085606
Disease: Urgency of micturition
Urgency of micturition 		40 0 12 0.21 0 0
CUI: C1271100
Disease: Lower limb spasticity
Lower limb spasticity 		43 0 12 0.20 0 0
CUI: C1849134
Disease: Impaired vibration sensation in the lower limbs
Impaired vibration sensation in the lower limbs 		39 0 11 0.20 0 0
CUI: C0751602
Disease: Hereditary Autosomal Dominant Spastic Paraplegia
Hereditary Autosomal Dominant Spastic Paraplegia 		27 0 9 0.20 0 0
CUI: C1846566
Disease: Degeneration of the lateral corticospinal tracts
Degeneration of the lateral corticospinal tracts 		21 0 8 0.20 0 0
CUI: C0393556
Disease: Complicated hereditary spastic paraplegia
Complicated hereditary spastic paraplegia 		16 0 6 0.16 0 0
CUI: C0238651
Disease: Ankle clonus
Ankle clonus 		32 0 8 0.15 0 0
CUI: C0271390
Disease: Nystagmus, End-Position
Nystagmus, End-Position 		26 0 7 0.15 0 0
CUI: C1836296
Disease: Muscle Weakness Lower Limb
Muscle Weakness Lower Limb 		74 0 13 0.15 0 0
CUI: C0037773
Disease: Spastic Paraplegia, Hereditary
Spastic Paraplegia, Hereditary 		123 0 19 0.14 0 0
CUI: C1836696
Disease: Lower limb hyperreflexia
Lower limb hyperreflexia 		38 0 8 0.14 0 0
CUI: C1295585
Disease: Decreased vibratory sense
Decreased vibratory sense 		33 0 7 0.13 0 0
CUI: C3711371
Disease: Spastic Paraplegia Type 4
Spastic Paraplegia Type 4 		7 0 4 0.13 0 0
CUI: C1866855
Disease: Spastic paraplegia 4, autosomal dominant
Spastic paraplegia 4, autosomal dominant 		10 0 4 0.12 0 0
CUI: C0037772
Disease: Spastic Paraplegia
Spastic Paraplegia 		144 0 18 0.12 0 0
CUI: C4025723
Disease: Abnormal upper motor neuron morphology
Abnormal upper motor neuron morphology 		20 0 5 0.12 0 0
CUI: C1836479
Disease: Saccadic smooth pursuit
Saccadic smooth pursuit 		22 0 5 0.11 0 0
CUI: C1842587
Disease: Sensory axonal neuropathy
Sensory axonal neuropathy 		23 0 5 0.11 0 0
CUI: C4024610
Disease: Leg muscle stiffness
Leg muscle stiffness 		13 0 4 0.11 0 0
CUI: C0037771
Disease: Paraparesis, Spastic
Paraparesis, Spastic 		75 0 10 0.11 0 0
CUI: C1849128
Disease: Spastic paraplegia 15, autosomal recessive
Spastic paraplegia 15, autosomal recessive 		3 0 3 0.11 0 0
CUI: C4021165
Disease: Abnormality of long bone morphology
Abnormality of long bone morphology 		3 0 3 0.11 0 0
CUI: C4023052
Disease: Ubiquitin-positive cerebral inclusion bodies
Ubiquitin-positive cerebral inclusion bodies 		3 0 3 0.11 0 0