Disease: 21-hydroxylase deficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CXADRP1 CXADR pseudogene 1 0.463 0.846
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
C4A P0C0L4 P0C0L5 complement C4A (Rodgers blood group) Enzyme modulator 1.5E-11 0.563 0.769
CYP3A4 P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 5.8E-11 0.462 0.885
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
HLA-DOA P06340 major histocompatibility complex, class II, DO alpha Immune response 3.0E-10 0.509 0.808
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
NR1I3 Q14994 nuclear receptor subfamily 1 group I member 3 Nuclear receptor 3.5E-08 0.448 0.846
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
TNXB P22105 tenascin XB 1.9E-02 0.572 0.731
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
ARR3 P36575 arrestin 3 Enzyme modulator 0.10 0.460 0.846
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
CXADR P78310 CXADR Ig-like cell adhesion molecule 0.37 0.454 0.885
FPR2 P25090 formyl peptide receptor 2 G-protein coupled receptor 0.40 0.547 0.769
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
TRIM13 O60858 tripartite motif containing 13 0.64 0.462 0.846
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
C4B P0C0L4 P0C0L5 complement C4B (Chido blood group) Enzyme modulator 0.83 0.603 0.808