Disease: 21-hydroxylase deficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CXADR P78310 CXADR Ig-like cell adhesion molecule 0.37 0.454 0.885
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
TNXB P22105 tenascin XB 1.9E-02 0.572 0.731
TRIM13 O60858 tripartite motif containing 13 0.64 0.462 0.846
CXADRP1 CXADR pseudogene 1 0.463 0.846
CYP3A4 P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 5.8E-11 0.462 0.885
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
ARR3 P36575 arrestin 3 Enzyme modulator 0.10 0.460 0.846
C4A P0C0L4 P0C0L5 complement C4A (Rodgers blood group) Enzyme modulator 1.5E-11 0.563 0.769
C4B P0C0L4 P0C0L5 complement C4B (Chido blood group) Enzyme modulator 0.83 0.603 0.808
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
FPR2 P25090 formyl peptide receptor 2 G-protein coupled receptor 0.40 0.547 0.769
HLA-DOA P06340 major histocompatibility complex, class II, DO alpha Immune response 3.0E-10 0.509 0.808
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846