Disease: Creutzfeldt-Jakob Disease, Sporadic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB6 Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 8.6E-19 0.431 0.885
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
AQP1 P29972 aquaporin 1 (Colton blood group) Ion channel 2.6E-07 0.467 0.885
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
C4BPA P04003 complement component 4 binding protein alpha 0.46 0.556 0.846
CARD14 Q9BXL6 caspase recruitment domain family member 14 1.2E-19 0.546 0.846
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CRYAB P02511 crystallin alpha B 2.2E-02 0.515 0.731
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
ENO2 P09104 enolase 2 Enzyme 0.38 0.475 0.846
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GPI P06744 glucose-6-phosphate isomerase Enzyme 2.8E-06 0.491 0.769
HECTD2 Q5U5R9 HECT domain E3 ubiquitin protein ligase 2 1.00 0.805 0.231
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MDH1 P40925 malate dehydrogenase 1 Enzyme 0.93 0.682 0.538
MUL1 Q969V5 mitochondrial E3 ubiquitin protein ligase 1 1.9E-06 0.473 0.808
NEFL P07196 neurofilament light 0.488 0.769
PLCXD3 Q63HM9 phosphatidylinositol specific phospholipase C X domain containing 3 8.9E-03 0.861 0.154