Disease: Joint hyperflexibility
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
ORC1 Q13415 origin recognition complex subunit 1 Nucleic acid binding 1.7E-14 0.595 0.654
ORC4 O43929 origin recognition complex subunit 4 Nucleic acid binding 7.6E-13 0.612 0.654
ARVCF O00192 ARVCF delta catenin family member Cellular structure 5.0E-11 0.540 0.769
CDT1 Q9H211 chromatin licensing and DNA replication factor 1 2.6E-10 0.597 0.731
CDC6 Q99741 cell division cycle 6 1.1E-09 0.552 0.731
ORC6 Q9Y5N6 origin recognition complex subunit 6 Nucleic acid binding 3.4E-07 0.628 0.577
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CANT1 Q8WVQ1 calcium activated nucleotidase 1 2.5E-06 0.619 0.731
CDC45 O75419 cell division cycle 45 Nucleic acid binding 4.6E-05 0.588 0.692
B4GALT7 Q9UBV7 beta-1,4-galactosyltransferase 7 1.1E-04 0.628 0.654
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
GMNN O75496 geminin DNA replication inhibitor 0.11 0.554 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
CRKL P46109 CRK like proto-oncogene, adaptor protein 0.45 0.553 0.769
GP1BB P13224 glycoprotein Ib platelet subunit beta 0.51 0.524 0.769
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
UFD1 Q92890 ubiquitin recognition factor in ER associated degradation 1 1.00 0.537 0.769
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
NFIX Q14938 nuclear factor I X Nucleic acid binding 1.00 0.547 0.769
LMNA P02545 lamin A/C 1.00 0.384 0.885
SATB2 Q9UPW6 SATB homeobox 2 Transcription factor 1.00 0.503 0.769
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846