Disease: Joint hyperflexibility
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ARVCF O00192 ARVCF delta catenin family member Cellular structure 5.0E-11 0.540 0.769
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
ORC4 O43929 origin recognition complex subunit 4 Nucleic acid binding 7.6E-13 0.612 0.654
CDC45 O75419 cell division cycle 45 Nucleic acid binding 4.6E-05 0.588 0.692
GMNN O75496 geminin DNA replication inhibitor 0.11 0.554 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
LMNA P02545 lamin A/C 1.00 0.384 0.885
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
GP1BB P13224 glycoprotein Ib platelet subunit beta 0.51 0.524 0.769
FLNA P21333 filamin A 1.00 0.419 0.846
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
CRKL P46109 CRK like proto-oncogene, adaptor protein 0.45 0.553 0.769
SEC24C P53992 SEC24 homolog C, COPII coat complex component Transporter 1.00 0.543 0.808
HIRA P54198 histone cell cycle regulator Nucleic acid binding 1.00 0.537 0.808
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
ORC1 Q13415 origin recognition complex subunit 1 Nucleic acid binding 1.7E-14 0.595 0.654