Disease: Bone Diseases
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALPL P05186 alkaline phosphatase, biomineralization associated Enzyme 3.6E-04 0.546 0.769
BEST1 O76090 bestrophin 1 Ion channel 1.8E-12 0.465 0.885
BGLAP P02818 bone gamma-carboxyglutamate protein 4.6E-08 0.462 0.846
BMP1 P13497 bone morphogenetic protein 1 8.9E-04 0.554 0.769
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
CRTAP O75718 cartilage associated protein Extracellular structure 5.5E-04 0.636 0.654
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
DMD P11532 dystrophin 1.00 0.423 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
LRP5 O75197 LDL receptor related protein 5 0.51 0.485 0.846
LRP6 O75581 LDL receptor related protein 6 0.70 0.536 0.808
MIR29B1 microRNA 29b-1 0.485 0.846
MIR29B2 microRNA 29b-2 0.484 0.885
P3H1 Q32P28 prolyl 3-hydroxylase 1 Extracellular structure 2.3E-20 0.736 0.231
PLS3 P13797 plastin 3 Cellular structure 0.99 0.656 0.500
PNPLA2 Q96AD5 patatin like phospholipase domain containing 2 Enzyme 4.1E-03 0.511 0.846
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
SERPINF1 P36955 serpin family F member 1 Enzyme modulator 7.8E-08 0.460 0.846
SERPINH1 P50454 serpin family H member 1 Enzyme modulator 2.8E-02 0.545 0.769
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
SOST Q9BQB4 sclerostin 0.87 0.474 0.808
SP7 Q8TDD2 Sp7 transcription factor Nucleic acid binding 0.58 0.711 0.462
SPARC P09486 secreted protein acidic and cysteine rich Signaling 0.89 0.445 0.846