Disease: Tonic - clonic seizures
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
GABRA1 P14867 gamma-aminobutyric acid type A receptor subunit alpha1 Ion channel 0.91 0.563 0.577
SIK1 A0A0B4J2F2 P57059 salt inducible kinase 1 Kinase 0.94 0.544 0.731
NEUROD2 Q15784 neuronal differentiation 2 Enzyme 0.94 0.619 0.538
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
GABRB3 P28472 gamma-aminobutyric acid type A receptor subunit beta3 Ion channel 0.95 0.546 0.615
GNAO1 P09471 G protein subunit alpha o1 Enzyme modulator 0.99 0.523 0.808
TRIM8 Q9BZR9 tripartite motif containing 8 0.99 0.588 0.731
CLCN4 P51793 chloride voltage-gated channel 4 Ion channel 1.00 0.587 0.654
DNM1 Q05193 dynamin 1 Enzyme modulator 1.00 0.595 0.692
GNB1 P62873 G protein subunit beta 1 Enzyme 1.00 0.617 0.731
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808
KCNQ2 O43526 potassium voltage-gated channel subfamily Q member 2 Ion channel 1.00 0.537 0.654
ALG13 Q9NP73 ALG13 UDP-N-acetylglucosaminyltransferase subunit 1.00 0.631 0.577
DLG3 Q92796 discs large MAGUK scaffold protein 3 1.00 0.544 0.615
CHD2 O14647 chromodomain helicase DNA binding protein 2 1.00 0.585 0.577
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
HNRNPU Q00839 heterogeneous nuclear ribonucleoprotein U 1.00 0.575 0.654
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808
SCN2A Q99250 sodium voltage-gated channel alpha subunit 2 Ion channel 1.00 0.518 0.731
STXBP1 P61764 syntaxin binding protein 1 Transporter 1.00 0.532 0.692