Disease: Paraparesis, Spastic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AAAS Q9NRG9 aladin WD repeat nucleoporin 2.4E-13 0.601 0.654
ABCD1 P33897 ATP binding cassette subfamily D member 1 Transporter 1.00 0.563 0.731
AFG3L2 Q9Y4W6 AFG3 like matrix AAA peptidase subunit 2 Enzyme 5.3E-09 0.588 0.462
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATXN3 P54252 ataxin 3 Enzyme 0.11 0.521 0.808
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
C19orf12 Q9NSK7 chromosome 19 open reading frame 12 0.34 0.641 0.615
CAPN1 P07384 calpain 1 Enzyme 5.9E-10 0.539 0.808
DDHD1 Q8NEL9 DDHD domain containing 1 Enzyme 0.90 0.716 0.423
DDHD2 O94830 DDHD domain containing 2 Enzyme 1.4E-10 0.695 0.577
DSTYK Q6XUX3 dual serine/threonine and tyrosine protein kinase Kinase 0.51 0.700 0.462
EPHB1 P54762 EPH receptor B1 Kinase 1.00 0.518 0.846
FA2H Q7L5A8 fatty acid 2-hydroxylase Enzyme 0.15 0.573 0.654
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
GJC2 Q5T442 gap junction protein gamma 2 Cell-cell junction 1.0E-02 0.593 0.692
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
KIF1C O43896 kinesin family member 1C Cellular structure 0.72 0.700 0.500
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
KY Q8NBH2 kyphoscoliosis peptidase 1.5E-10 0.736 0.231
MAG P20916 myelin associated glycoprotein Receptor 0.49 0.579 0.692
PCYT2 Q99447 phosphate cytidylyltransferase 2, ethanolamine Enzyme 8.6E-04 0.821 0.192
PLP1 P60201 proteolipid protein 1 Cellular structure 0.93 0.543 0.769
REEP1 Q9H902 receptor accessory protein 1 Transporter 0.99 0.653 0.423