Disease: Substance Use Disorders
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SSTR4 P31391 somatostatin receptor 4 G-protein coupled receptor 3.7E-13 0.469 0.846
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
ADRA1A P35348 adrenoceptor alpha 1A G-protein coupled receptor 3.4E-07 0.462 0.846
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
ADRA2B P18089 adrenoceptor alpha 2B G-protein coupled receptor 4.5E-06 0.465 0.846
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
CXCR6 O00574 C-X-C motif chemokine receptor 6 G-protein coupled receptor 5.7E-05 0.448 0.885
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
OPRD1 P41143 opioid receptor delta 1 G-protein coupled receptor 3.3E-03 0.604 0.731
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
LPAR2 Q9HBW0 lysophosphatidic acid receptor 2 G-protein coupled receptor 3.7E-02 0.463 0.846
GPR42 O15529 G protein-coupled receptor 42 (gene/pseudogene) G-protein coupled receptor 5.1E-02 0.475 0.846
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
CHRNB4 P30926 cholinergic receptor nicotinic beta 4 subunit Ion channel 0.14 0.644 0.423
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
ACKR3 P25106 atypical chemokine receptor 3 G-protein coupled receptor 0.39 0.428 0.885