Disease: Substance Use Disorders
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
CXCR6 O00574 C-X-C motif chemokine receptor 6 G-protein coupled receptor 5.7E-05 0.448 0.885
GPR42 O15529 G protein-coupled receptor 42 (gene/pseudogene) G-protein coupled receptor 5.1E-02 0.475 0.846
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
SNAP91 O60641 synaptosome associated protein 91 Transporter 1.00 0.638 0.538
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
CALM1 P0DP23 P0DP24 P0DP25 calmodulin 1 Calcium-binding protein 0.94 0.472 0.808
CALM2 P0DP23 P0DP24 P0DP25 calmodulin 2 Calcium-binding protein 0.92 0.472 0.808
CALM3 P0DP23 P0DP24 P0DP25 calmodulin 3 Calcium-binding protein 0.93 0.485 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
ADRA2B P18089 adrenoceptor alpha 2B G-protein coupled receptor 4.5E-06 0.465 0.846
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
ACKR3 P25106 atypical chemokine receptor 3 G-protein coupled receptor 0.39 0.428 0.885
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CHRNB4 P30926 cholinergic receptor nicotinic beta 4 subunit Ion channel 0.14 0.644 0.423