Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
SORT1 Q99523 sortilin 1 Transporter 1.00 0.573 0.615
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
ARNTL O00327 aryl hydrocarbon receptor nuclear translocator like Transcription factor 0.99 0.510 0.885
IKBKB O14920 inhibitor of nuclear factor kappa B kinase subunit beta Kinase 0.99 0.506 0.846
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
HNF1A P20823 HNF1 homeobox A Nucleic acid binding 0.96 0.478 0.846
CD40 P25942 CD40 molecule 0.85 0.396 0.846
PLA2G15 Q8NCC3 phospholipase A2 group XV Enzyme 0.38 0.520 0.769
MYLIP Q8WY64 myosin regulatory light chain interacting protein 0.18 0.582 0.692
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
SCARB1 Q8WTV0 scavenger receptor class B member 1 Receptor 6.6E-02 0.559 0.731
INSIG2 Q9Y5U4 insulin induced gene 2 6.0E-02 0.653 0.500
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
NR1H4 Q96RI1 nuclear receptor subfamily 1 group H member 4 Nuclear receptor 9.4E-04 0.513 0.808
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846