Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885
HNF1A P20823 HNF1 homeobox A Nucleic acid binding 0.96 0.478 0.846
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
GSR P00390 glutathione-disulfide reductase Enzyme 1.3E-06 0.494 0.846
FGFR4 P22455 fibroblast growth factor receptor 4 Kinase 7.2E-13 0.490 0.769
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
CYP4F2 P78329 cytochrome P450 family 4 subfamily F member 2 Enzyme 7.6E-17 0.674 0.308
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
CD40 P25942 CD40 molecule 0.85 0.396 0.846
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
ARNTL O00327 aryl hydrocarbon receptor nuclear translocator like Transcription factor 0.99 0.510 0.885
ARG1 P05089 arginase 1 Enzyme 3.6E-04 0.476 0.846
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
ANGPTL3 Q9Y5C1 angiopoietin like 3 Signaling 1.6E-13 0.584 0.577
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885