Disease: Adrenal Cushing's syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACAT1 P24752 acetyl-CoA acetyltransferase 1 Enzyme 9.9E-08 0.538 0.692
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
AKR1B1 P15121 aldo-keto reductase family 1 member B Enzyme 2.0E-05 0.491 0.885
ARMC5 Q96C12 armadillo repeat containing 5 0.11 0.670 0.500
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CYP11B1 P15538 cytochrome P450 family 11 subfamily B member 1 8.2E-07 0.563 0.615
CYP11B2 P19099 cytochrome P450 family 11 subfamily B member 2 7.1E-19 0.553 0.615
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846
FH P07954 fumarate hydratase Enzyme 8.8E-02 0.489 0.846
FOLH1 Q04609 folate hydrolase 1 Enzyme 6.2E-09 0.453 0.885
GHSR Q92847 growth hormone secretagogue receptor G-protein coupled receptor 6.6E-03 0.528 0.769
GIPR P48546 gastric inhibitory polypeptide receptor G-protein coupled receptor 2.0E-29 0.670 0.538
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
KCNJ5 P48544 potassium inwardly rectifying channel subfamily J member 5 Ion channel 3.4E-04 0.560 0.577
LEP P41159 leptin 0.46 0.349 0.846
LGR6 Q9HBX8 leucine rich repeat containing G protein-coupled receptor 6 G-protein coupled receptor 2.9E-06 0.502 0.923
LHCGR P22888 luteinizing hormone/choriogonadotropin receptor G-protein coupled receptor 5.3E-08 0.528 0.692
MC2R Q01718 melanocortin 2 receptor G-protein coupled receptor 3.1E-04 0.582 0.654
MEN1 O00255 menin 1 1.00 0.444 0.808