Disease: Ichthyosis, X-Linked
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CD8A P01732 CD8a molecule 1.7E-05 0.587 0.769
CHEK1 O14757 checkpoint kinase 1 Kinase 3.1E-08 0.492 0.808
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
EPHB4 P54760 EPH receptor B4 Kinase 1.3E-02 0.524 0.692
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
GLB1 P16278 galactosidase beta 1 Enzyme 7.9E-10 0.448 0.808
LGALS1 P09382 galectin 1 Signaling 4.5E-03 0.435 0.846