Disease: Ichthyosis, X-Linked
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EPHB4 P54760 EPH receptor B4 Kinase 1.3E-02 0.524 0.692
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
CD8A P01732 CD8a molecule 1.7E-05 0.587 0.769
MLRL Myeloid leukemia-related gene (myeloid tumor suppressor) 0.564 0.769
CHEK1 O14757 checkpoint kinase 1 Kinase 3.1E-08 0.492 0.808
GLB1 P16278 galactosidase beta 1 Enzyme 7.9E-10 0.448 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
NME1 P15531 NME/NM23 nucleoside diphosphate kinase 1 Kinase 3.2E-03 0.443 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
LGALS1 P09382 galectin 1 Signaling 4.5E-03 0.435 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
TIMP2 P16035 TIMP metallopeptidase inhibitor 2 Enzyme modulator 0.79 0.425 0.846
VIM P08670 vimentin 0.71 0.372 0.846
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885