Disease: FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
FANCI Q9NVI1 FA complementation group I 8.9E-37 0.543 0.731
FANCL Q9NW38 FA complementation group L Enzyme 5.9E-23 0.551 0.731
FANCM Q8IYD8 FA complementation group M Enzyme 2.4E-15 0.543 0.731
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
NLRP2 Q9NX02 NLR family pyrin domain containing 2 1.4E-38 0.515 0.731
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
PPM1D O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D Enzyme 2.2E-11 0.513 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923