Disease: Familial Alzheimer Disease (FAD)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TAS2R62P taste 2 receptor member 62 pseudogene 0.729 0.192
SLC30A6 Q6NXT4 solute carrier family 30 member 6 Transporter 6.9E-09 0.711 0.346
ESCO1 Q5FWF5 establishment of sister chromatid cohesion N-acetyltransferase 1 1.00 0.682 0.462
ADI1 Q9BV57 acireductone dioxygenase 1 Enzyme 3.2E-05 0.674 0.654
NCSTN Q92542 nicastrin 1.00 0.666 0.462
LRP8 Q14114 LDL receptor related protein 8 1.00 0.644 0.346
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
NFIC P08651 nuclear factor I C Nucleic acid binding 9.1E-02 0.626 0.654
KCNIP3 Q9Y2W7 potassium voltage-gated channel interacting protein 3 Ion channel 3.8E-02 0.626 0.654
CHRNB2 P17787 cholinergic receptor nicotinic beta 2 subunit Ion channel 7.3E-04 0.617 0.308
ITM2B Q9Y287 integral membrane protein 2B 0.63 0.617 0.654
CASP6 P55212 caspase 6 Enzyme 1.3E-04 0.610 0.615
NRGN Q92686 neurogranin 0.48 0.608 0.615
IDE P14735 insulin degrading enzyme Enzyme 6.6E-03 0.604 0.577
NFIA Q12857 nuclear factor I A Nucleic acid binding 1.00 0.599 0.808
DLG4 P78352 discs large MAGUK scaffold protein 4 Receptor 1.00 0.595 0.654
PICALM Q13492 phosphatidylinositol binding clathrin assembly protein Transporter 1.00 0.592 0.538
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
APOC1 P02654 apolipoprotein C1 0.22 0.581 0.577
SYNJ1 O43426 synaptojanin 1 Enzyme 0.43 0.576 0.577
NECTIN2 Q92692 nectin cell adhesion molecule 2 0.97 0.575 0.769
NFIB O00712 nuclear factor I B Nucleic acid binding 1.00 0.573 0.654
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769