Disease: Familial Alzheimer Disease (FAD)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
INPP5D Q92835 inositol polyphosphate-5-phosphatase D 0.97 0.558 0.731
CD2AP Q9Y5K6 CD2 associated protein 0.23 0.558 0.731
TPP1 O14773 tripeptidyl peptidase 1 Enzyme 6.3E-07 0.551 0.808
BIN1 O00499 bridging integrator 1 0.78 0.550 0.692
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
NFIX Q14938 nuclear factor I X Nucleic acid binding 1.00 0.547 0.769
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
TRPM7 Q96QT4 transient receptor potential cation channel subfamily M member 7 Ion channel 5.2E-16 0.531 0.731
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
TFAM Q00059 transcription factor A, mitochondrial 0.17 0.529 0.731
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TPI1 P60174 triosephosphate isomerase 1 Enzyme 3.0E-02 0.517 0.846
RELN P78509 reelin 1.00 0.515 0.731
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
PEBP1 P30086 phosphatidylethanolamine binding protein 1 Enzyme modulator 9.2E-02 0.500 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
IL12A P29459 interleukin 12A 4.7E-02 0.491 0.808
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
NEFL P07196 neurofilament light 0.488 0.769
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
KNG1 P01042 kininogen 1 Enzyme modulator 3.2E-10 0.481 0.885
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846