Disease: Muscle Spasticity
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EIF2B1 Q14232 eukaryotic translation initiation factor 2B subunit alpha 7.6E-05 0.663 0.538
EPRS1 P07814 glutamyl-prolyl-tRNA synthetase 1 Enzyme 1.0E-09 0.644 0.538
GRIK3 Q13003 glutamate ionotropic receptor kainate type subunit 3 Ion channel 1.00 0.674 0.538
GRIN2D O15399 glutamate ionotropic receptor NMDA type subunit 2D Ion channel 1.00 0.650 0.538
RARS1 P54136 arginyl-tRNA synthetase 1 3.3E-08 0.604 0.538
EIF2B4 Q9UI10 eukaryotic translation initiation factor 2B subunit delta 0.96 0.659 0.538
EIF2B2 P49770 eukaryotic translation initiation factor 2B subunit beta 2.1E-10 0.647 0.538
MACF1 Q9UPN3 microtubule actin crosslinking factor 1 Cellular structure 1.00 0.659 0.538
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
AMPD2 Q01433 adenosine monophosphate deaminase 2 Enzyme 4.5E-07 0.663 0.577
GLE1 Q53GS7 GLE1 RNA export mediator Transporter 2.1E-10 0.628 0.577
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
IREB2 P48200 iron responsive element binding protein 2 Enzyme 1.00 0.619 0.577
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
EPM2A O95278 EPM2A glucan phosphatase, laforin 8.7E-06 0.608 0.577
SYNJ1 O43426 synaptojanin 1 Enzyme 0.43 0.576 0.577
CACNA1G O43497 calcium voltage-gated channel subunit alpha1 G Ion channel 1.00 0.590 0.577
ATP13A2 Q9NQ11 ATPase cation transporting 13A2 9.0E-09 0.566 0.577
PCLO Q9Y6V0 piccolo presynaptic cytomatrix protein 1.00 0.656 0.577
DARS2 Q6PI48 aspartyl-tRNA synthetase 2, mitochondrial Enzyme 9.8E-13 0.638 0.577
NARS2 Q96I59 asparaginyl-tRNA synthetase 2, mitochondrial Enzyme 7.1E-08 0.650 0.577
SGCG Q13326 sarcoglycan gamma Cellular structure 4.8E-05 0.621 0.615
TUBB4A P04350 tubulin beta 4A class IVa Cellular structure 0.11 0.608 0.615
SLC39A14 Q15043 solute carrier family 39 member 14 Transporter 0.15 0.653 0.615
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654