Disease: Disorder of the optic nerve
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
PAX6 P26367 paired box 6 1.00 0.450 0.769
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
NEFL P07196 neurofilament light 0.488 0.769
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
WFS1 O76024 wolframin ER transmembrane glycoprotein 1.6E-38 0.528 0.846
CYTB P00156 cytochrome b 0.529 0.808
ND5 P03915 NADH dehydrogenase, subunit 5 (complex I) Enzyme 0.531 0.769
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
ND4 P03905 NADH dehydrogenase, subunit 4 (complex I) Enzyme 0.546 0.769
NDUFA13 Q9P0J0 NADH:ubiquinone oxidoreductase subunit A13 Enzyme 3.8E-06 0.556 0.692
NDUFB11 Q9NX14 NADH:ubiquinone oxidoreductase subunit B11 Enzyme 0.80 0.566 0.692
OPN4 Q9UHM6 opsin 4 G-protein coupled receptor 9.0E-13 0.579 0.769
NDUFS7 O75251 NADH:ubiquinone oxidoreductase core subunit S7 0.91 0.579 0.769
NDUFS3 O75489 NADH:ubiquinone oxidoreductase core subunit S3 5.8E-04 0.581 0.769
NDUFS4 O43181 NADH:ubiquinone oxidoreductase subunit S4 3.1E-04 0.587 0.808
NDUFS1 P28331 NADH:ubiquinone oxidoreductase core subunit S1 Enzyme 6.6E-11 0.595 0.692