Disease: Disorder of the optic nerve
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NDUFS8 O00217 NADH:ubiquinone oxidoreductase core subunit S8 Enzyme 0.17 0.636 0.538
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
NDUFA1 O15239 NADH:ubiquinone oxidoreductase subunit A1 0.55 0.636 0.423
NDUFS4 O43181 NADH:ubiquinone oxidoreductase subunit S4 3.1E-04 0.587 0.808
NDUFB3 O43676 NADH:ubiquinone oxidoreductase subunit B3 1.6E-05 0.705 0.538
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
NDUFS7 O75251 NADH:ubiquinone oxidoreductase core subunit S7 0.91 0.579 0.769
NDUFS2 O75306 NADH:ubiquinone oxidoreductase core subunit S2 Enzyme 1.4E-03 0.601 0.654
NDUFS6 O75380 NADH:ubiquinone oxidoreductase subunit S6 Enzyme 9.6E-02 0.686 0.423
NDUFS3 O75489 NADH:ubiquinone oxidoreductase core subunit S3 5.8E-04 0.581 0.769
WFS1 O76024 wolframin ER transmembrane glycoprotein 1.6E-38 0.528 0.846
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
CYTB P00156 cytochrome b 0.529 0.808
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
ND3 P03897 NADH dehydrogenase, subunit 3 (complex I) 0.604 0.654
ND4 P03905 NADH dehydrogenase, subunit 4 (complex I) Enzyme 0.546 0.769
ND5 P03915 NADH dehydrogenase, subunit 5 (complex I) Enzyme 0.531 0.769
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
NEFL P07196 neurofilament light 0.488 0.769
PAX6 P26367 paired box 6 1.00 0.450 0.769
NDUFS1 P28331 NADH:ubiquinone oxidoreductase core subunit S1 Enzyme 6.6E-11 0.595 0.692
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923