Disease: Keratoderma, Palmoplantar
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRT6C P48668 keratin 6C 3.8E-22 0.751 0.269
KRT9 P35527 keratin 9 1.1E-06 0.678 0.346
POMP Q9Y244 proteasome maturation protein 0.91 0.674 0.346
EVPL Q92817 envoplakin Cellular structure 5.7E-25 0.599 0.423
LORICRIN P23490 loricrin cornified envelope precursor protein 0.33 0.674 0.423
SMARCAD1 Q9H4L7 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 Enzyme 1.00 0.656 0.423
NIPAL4 Q0D2K0 NIPA like domain containing 4 1.4E-03 0.682 0.423
GJB3 O75712 gap junction protein beta 3 Cell-cell junction 2.2E-03 0.621 0.462
DSG1 Q02413 desmoglein 1 Cell adhesion 0.93 0.606 0.538
ALOXE3 Q9BYJ1 arachidonate lipoxygenase 3 Enzyme 5.1E-20 0.644 0.538
RHBDF2 Q6PJF5 rhomboid 5 homolog 2 Enzyme 1.2E-03 0.595 0.538
ALOX12B O75342 arachidonate 12-lipoxygenase, 12R type Enzyme 7.6E-04 0.603 0.577
TRPV3 Q8NET8 transient receptor potential cation channel subfamily V member 3 Ion channel 4.6E-20 0.610 0.577
KRT1 P04264 keratin 1 0.74 0.575 0.654
ABCA12 Q86UK0 ATP binding cassette subfamily A member 12 Transporter 2.9E-15 0.610 0.654
SLURP1 P55000 secreted LY6/PLAUR domain containing 1 0.26 0.560 0.654
KLKB1 P03952 kallikrein B1 Enzyme 6.3E-13 0.604 0.692
KRT6A P02538 keratin 6A 7.0E-05 0.610 0.692
KRT10 P13645 keratin 10 2.5E-03 0.579 0.692
SRD5A3 Q9H8P0 steroid 5 alpha-reductase 3 2.5E-04 0.604 0.692
CTSC P53634 cathepsin C Enzyme 1.1E-07 0.541 0.731
KRT5 P13647 keratin 5 0.64 0.512 0.731
KRT14 P02533 keratin 14 2.0E-04 0.530 0.731
KRT16 P08779 keratin 16 1.5E-14 0.565 0.769
TGM1 P22735 transglutaminase 1 Enzyme 2.3E-13 0.565 0.769