Disease: Keratoderma, Palmoplantar
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769
ALOX12B O75342 arachidonate 12-lipoxygenase, 12R type Enzyme 7.6E-04 0.603 0.577
GJB3 O75712 gap junction protein beta 3 Cell-cell junction 2.2E-03 0.621 0.462
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
KRT14 P02533 keratin 14 2.0E-04 0.530 0.731
KRT6A P02538 keratin 6A 7.0E-05 0.610 0.692
KLKB1 P03952 kallikrein B1 Enzyme 6.3E-13 0.604 0.692
KRT1 P04264 keratin 1 0.74 0.575 0.654
KRT16 P08779 keratin 16 1.5E-14 0.565 0.769
CD28 P10747 CD28 molecule 0.36 0.436 0.885
KRT10 P13645 keratin 10 2.5E-03 0.579 0.692
KRT5 P13647 keratin 5 0.64 0.512 0.731
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
TAT P17735 tyrosine aminotransferase 6.9E-03 0.492 0.846
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
ENPP1 P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 5.0E-08 0.498 0.808
TGM1 P22735 transglutaminase 1 Enzyme 2.3E-13 0.565 0.769
LORICRIN P23490 loricrin cornified envelope precursor protein 0.33 0.674 0.423
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846