Disease: Frontotemporal dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MSMB P08118 microseminoprotein beta Signaling 1.6E-02 0.498 0.846
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
RIDA P52758 reactive intermediate imine deaminase A homolog 6.8E-02 0.606 0.769
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
TIA1 P31483 TIA1 cytotoxic granule associated RNA binding protein 0.27 0.595 0.577
LEP P41159 leptin 0.46 0.349 0.846
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
PIN1 Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.74 0.488 0.769
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
TTBK2 Q6IQ55 tau tubulin kinase 2 Kinase 1.00 0.682 0.423