Disease: Cancer cachexia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
FADD Q13158 Fas associated via death domain 0.53 0.537 0.846
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
LIF P15018 LIF interleukin 6 family cytokine Signaling 0.52 0.483 0.769
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962