Disease: Sporadic Breast Carcinoma
Source: BEFREE ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PMS1 P54277 PMS1 homolog 1, mismatch repair system component Nucleic acid binding 1.3E-17 0.569 0.654
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
NLRP2 Q9NX02 NLR family pyrin domain containing 2 1.4E-38 0.515 0.731
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
CTCF P49711 CCCTC-binding factor Transcription factor 1.00 0.504 0.769
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
CDH1 P12830 cadherin 1 0.15 0.401 0.808
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846
DNMT3B Q9UBC3 DNA methyltransferase 3 beta 0.20 0.453 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885