Source: BEFREE ×
Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ARID1A | O14497 | AT-rich interaction domain 1A | 1.00 | 0.455 | 0.846 | |
RAD51C | O43502 | RAD51 paralog C | 6.2E-14 | 0.533 | 0.692 | |
NBN | O60934 | nibrin | Nucleic acid binding | 2.2E-16 | 0.467 | 0.808 |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
CYP1A1 | P04798 | cytochrome P450 family 1 subfamily A member 1 | Enzyme | 1.1E-17 | 0.436 | 0.846 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
GSTP1 | P09211 | glutathione S-transferase pi 1 | 1.4E-02 | 0.383 | 0.923 | |
GSTM1 | P09488 | glutathione S-transferase mu 1 | 2.1E-03 | 0.380 | 0.923 | |
PARP1 | P09874 | poly(ADP-ribose) polymerase 1 | 3.3E-04 | 0.389 | 0.923 | |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
COL11A2 | P13942 | collagen type XI alpha 2 chain | 0.70 | 0.435 | 0.846 | |
CTLA4 | P16410 | cytotoxic T-lymphocyte associated protein 4 | 0.94 | 0.369 | 0.923 | |
ERCC2 | P18074 | ERCC excision repair 2, TFIIH core complex helicase subunit | Enzyme | 7.1E-20 | 0.420 | 0.846 |
MSH3 | P20585 | mutS homolog 3 | Nucleic acid binding | 7.4E-31 | 0.474 | 0.769 |
COMT | P21964 | catechol-O-methyltransferase | Enzyme | 1.1E-06 | 0.400 | 0.923 |
MRC1 | P22897 | mannose receptor C-type 1 | 0.94 | 0.413 | 0.846 | |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 |