Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846
TUBB3 Q13509 tubulin beta 3 class III Cellular structure 2.6E-10 0.486 0.808
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
POLR3A O14802 RNA polymerase III subunit A Enzyme 1.3E-23 0.538 0.769
CAPN1 P07384 calpain 1 Enzyme 5.9E-10 0.539 0.808
PLP1 P60201 proteolipid protein 1 Cellular structure 0.93 0.543 0.769
PRDX5 P30044 peroxiredoxin 5 1.8E-04 0.522 0.808
PDXP Q96GD0 pyridoxal phosphatase Enzyme 0.26 0.533 0.731
TBCE Q15813 tubulin folding cofactor E Chaperone 1.7E-08 0.575 0.692
VAMP1 P23763 vesicle associated membrane protein 1 3.9E-03 0.628 0.538
AFG3L2 Q9Y4W6 AFG3 like matrix AAA peptidase subunit 2 Enzyme 5.3E-09 0.588 0.462
CACNA1G O43497 calcium voltage-gated channel subunit alpha1 G Ion channel 1.00 0.590 0.577
SACS Q9NZJ4 sacsin molecular chaperone 1.1E-23 0.606 0.654
MTPAP Q9NVV4 mitochondrial poly(A) polymerase Enzyme 1.00 0.581 0.769
AAAS Q9NRG9 aladin WD repeat nucleoporin 2.4E-13 0.601 0.654
DARS2 Q6PI48 aspartyl-tRNA synthetase 2, mitochondrial Enzyme 9.8E-13 0.638 0.577
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
GLRX5 Q86SX6 glutaredoxin 5 Enzyme 0.75 0.659 0.538
KIF1C O43896 kinesin family member 1C Cellular structure 0.72 0.700 0.500
NKX6-2 Q9C056 NK6 homeobox 2 Transcription factor 2.9E-02 0.695 0.500
MARS2 Q96GW9 methionyl-tRNA synthetase 2, mitochondrial Enzyme 5.4E-05 0.682 0.538
PRDM8 Q9NQV8 PR/SET domain 8 0.78 0.678 0.462
DDHD2 O94830 DDHD domain containing 2 Enzyme 1.4E-10 0.695 0.577