Disease: Dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846