Disease: Dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
PITX3 O75364 paired like homeodomain 3 0.81 0.585 0.692
SNCG O76070 synuclein gamma Transporter 8.5E-04 0.550 0.615
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
GAPDH P04406 glyceraldehyde-3-phosphate dehydrogenase Enzyme 0.11 0.447 0.808
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
GPX1 P07203 glutathione peroxidase 1 Enzyme 3.9E-05 0.458 0.923
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885