Gene: ABCB1 ×
Source: BEFREE ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1128503
rs1128503
ABCB1
0.030 GeneticVariation BEFREE Here, we performed a meta-analysis to assess whether ABCB1 polymorphisms 3435C > T (rs1045642), 2677G > T/A (rs2032582), 1236C > T (rs1128503) and haplotypes were associated with AD risk. 27600024

2016
dbSNP: rs1128503
rs1128503
ABCB1
0.030 GeneticVariation BEFREE To evaluate the association of ATP-binding cassette subfamily B member 1 (ABCB1) genetic variants with the susceptibility to Alzheimer's disease (AD), we genotyped the rs1128503 (C1236T), rs2032582 (G2677T/A), and rs1045642 (C3435T) polymorphisms in a case-control sample (234 AD patients, 225 controls). 25273678

2014
dbSNP: rs1128503
rs1128503
ABCB1
0.030 GeneticVariation BEFREE Fifty-four Italian patients diagnosed with probable mild to moderate Alzheimer's disease, treated with donepezil (37 patients 5 mg/day, 17 patients 10 mg/day) were genotyped for CYP3A4 (*1B, *3, and *4), CYP3A5 (*2, *3, and *6) and ABCB1 (3435C>T, 2677G>T/A, and 1236C>T) polymorphisms. 20931330

2011
dbSNP: rs1045642
rs1045642
ABCB1
0.020 GeneticVariation BEFREE Our results suggest that the ABCB1 3435C > T SNP, the 2677G > T/A SNP and 1236T/2677T/3435C haplotype are significantly associated with AD susceptibility. 27600024

2016
dbSNP: rs2032582
rs2032582
ABCB1
0.020 GeneticVariation BEFREE Our results suggest that the ABCB1 3435C > T SNP, the 2677G > T/A SNP and 1236T/2677T/3435C haplotype are significantly associated with AD susceptibility. 27600024

2016
dbSNP: rs1045642
rs1045642
ABCB1
0.020 GeneticVariation BEFREE Single-marker analyses revealed a significant association solely for the rs1045642 polymorphism (C/C genotype carriers had increased risk for AD), which remains significant after correction for multiple testing. 25273678

2014
dbSNP: rs2032582
rs2032582
ABCB1
0.020 GeneticVariation BEFREE To evaluate the association of ATP-binding cassette subfamily B member 1 (ABCB1) genetic variants with the susceptibility to Alzheimer's disease (AD), we genotyped the rs1128503 (C1236T), rs2032582 (G2677T/A), and rs1045642 (C3435T) polymorphisms in a case-control sample (234 AD patients, 225 controls). 25273678

2014
dbSNP: rs1404008939
rs1404008939
ABCB1
0.010 GeneticVariation BEFREE However, only ABCC2 3972C>T (rs3740066) was significantly associated with AD risk after logistic regression analysis including all variants. 23556446

2013