Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.050 | GeneticVariation | BEFREE | While allelic variation in BDNF Val66Met may influence Aβ+ related neurodegeneration and memory loss over the short term, this is not related to serum mBDNF. | 28720165 | 2017 |
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0.050 | GeneticVariation | BEFREE | To examine the influence of the brain-derived neurotrophic factor (<i>BDNF</i>) Val66Met polymorphism on longitudinal cognitive trajectories in a large, cognitively healthy cohort enriched for Alzheimer disease (AD) risk and to understand whether β-amyloid (Aβ) burden plays a moderating role in this relationship. | 28468845 | 2017 |
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0.050 | GeneticVariation | BEFREE | While allelic variation in BDNF Val66Met may influence Aβ+ related neurodegeneration and memory loss over the short term, this is not related to serum mBDNF. | 28720165 | 2017 |
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0.050 | GeneticVariation | BEFREE | To examine the influence of the brain-derived neurotrophic factor (<i>BDNF</i>) Val66Met polymorphism on longitudinal cognitive trajectories in a large, cognitively healthy cohort enriched for Alzheimer disease (AD) risk and to understand whether β-amyloid (Aβ) burden plays a moderating role in this relationship. | 28468845 | 2017 |
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0.050 | GeneticVariation | BEFREE | Among Aβ+ women, ε4 carriers reported greater anxiety symptoms than non-ε4 carriers (d = 0.83), and female BDNF rs6265 Val66 Met allele carriers reported greater depressive symptoms (d = 0.29). | 27742526 | 2016 |
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0.050 | GeneticVariation | BEFREE | We aimed to determine the effect of BDNF Val66Met on cognitive function, hippocampal function, tau and amyloid-β in preclinical autosomal dominant Alzheimer's disease. | 27521573 | 2016 |
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0.050 | GeneticVariation | BEFREE | Among Aβ+ women, ε4 carriers reported greater anxiety symptoms than non-ε4 carriers (d = 0.83), and female BDNF rs6265 Val66 Met allele carriers reported greater depressive symptoms (d = 0.29). | 27742526 | 2016 |
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0.050 | GeneticVariation | BEFREE | We aimed to determine the effect of BDNF Val66Met on cognitive function, hippocampal function, tau and amyloid-β in preclinical autosomal dominant Alzheimer's disease. | 27521573 | 2016 |
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0.050 | GeneticVariation | BEFREE | BDNF Val66Met did not relate to the amount of Aβ or to the rate of Aβ accumulation in either group. | 23769397 | 2013 |
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0.050 | GeneticVariation | BEFREE | BDNF Val66Met did not relate to the amount of Aβ or to the rate of Aβ accumulation in either group. | 23769397 | 2013 |