|
rs4869317
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphisms (SNPs) of the following genes: oxytocin receptor (rs2254298, rs53576), OXT (rs6133010), OXT-arginine-vasopressin (rs2740204), CD38 (rs6449197, rs3796863), and human leucyl/cystinylaminopeptidase (rs4869317) were genotyped in 60 AN female inpatients and 60 healthy control females (HCs).
|
31385420 |
2019 |
|
rs2254298
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This pilot study suggests that in anorexia nervosa, differences related to <i>OXTR</i> SNP rs2254298 may alter neural responses to social stimuli and disrupt the engagement and disengagement of the default mode network.
|
30542304 |
2018 |
|
rs923768
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For a single nucleotide polymorphism rs923768 in CSGALNACT1 a nearby site was nominally associated with AN.
|
27367046 |
2018 |
|
rs10052957
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association of five polymorphisms (rs6191, rs258813, rs33388, rs41423247 and rs10052957) and one complex allele (TCAGT) of NR3C1 gene with increased risk of AN were found.
|
26938822 |
2016 |
|
rs1800497
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We concluded that rs1800497 and rs4633 play important roles in the AN susceptibility with respect to the Chinese Han population.
|
26808641 |
2016 |
|
rs33388
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association of five polymorphisms (rs6191, rs258813, rs33388, rs41423247 and rs10052957) and one complex allele (TCAGT) of NR3C1 gene with increased risk of AN were found.
|
26938822 |
2016 |
|
rs41423247
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association of five polymorphisms (rs6191, rs258813, rs33388, rs41423247 and rs10052957) and one complex allele (TCAGT) of NR3C1 gene with increased risk of AN were found.
|
26938822 |
2016 |
|
rs4633
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We concluded that rs1800497 and rs4633 play important roles in the AN susceptibility with respect to the Chinese Han population.
|
26808641 |
2016 |
|
rs4818
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this work is to explore the roles of DRD2 (rs1800497) and COMT (rs4680, rs4633, rs4818) gene polymorphisms in the susceptibility of AN within the Chinese Han population.
|
26808641 |
2016 |
|
rs1042571
|
|
|
0.010 |
GeneticVariation |
BEFREE |
AGRP rs13338499 polymorphism was associated with lowest illness-related BMI in those with AN (p = 0.0013), and NTRK2 rs1042571 was associated with highest BMI in those with BN (p = 0.0018).
|
24831852 |
2014 |
|
rs13338499
|
|
|
0.010 |
GeneticVariation |
BEFREE |
AGRP rs13338499 polymorphism was associated with lowest illness-related BMI in those with AN (p = 0.0013), and NTRK2 rs1042571 was associated with highest BMI in those with BN (p = 0.0018).
|
24831852 |
2014 |
|
rs3798577
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An eight-SNP haplotype at the estrogen receptor I (ESR1) gene was found to be associated with anorexia nervosa (AN) (Versini et al., Neuropsychopharmacology, 35, 1818-1825, 2010) and three SNPs from this haplotype (rs726281, rs2295193, and rs3798577) were associated with AN and/or EDs.
|
24282178 |
2014 |
|
rs10070190
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD.
|
23337130 |
2013 |
|
rs11179027
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, rs3825885 (NTRK3, p = 9 × 10(-4)) was identified as an AN risk variant, and rs11179027 (TPH2, p = 2 × 10(-3)) as an OCD marker.
|
23337130 |
2013 |
|
rs11783752
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD.
|
23337130 |
2013 |
|
rs2834070
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD.
|
23337130 |
2013 |
|
rs3825885
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, rs3825885 (NTRK3, p = 9 × 10(-4)) was identified as an AN risk variant, and rs11179027 (TPH2, p = 2 × 10(-3)) as an OCD marker.
|
23337130 |
2013 |
|
rs4825476
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD.
|
23337130 |
2013 |
|
rs774996029
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Anorexia nervosa and the Val158Met polymorphism of the COMT gene: meta-analysis and new data.
|
22366815 |
2012 |
|
rs9939609
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, compared to both control groups, we further detected a nominal association of the rs9939609 A-allele to AN (OR = 1.181, 95% CI 1.027-1.359, two-sided p = 0.020 or OR = 1.673, 95% CI 1.101-2.541, two-sided p = 0.015,).
|
22797368 |
2012 |
|
rs10096097
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based on a recessive mode of inheritance we observed some evidence for association of the G/G genotype at SNP rs10096097 with AN (nominal two-sided p = 0.031).
|
21035823 |
2011 |
|
rs3749073
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An association between the functional Gly195Val polymorphism and anorexia nervosa was tested in a female Japanese population comprising 235 patients and 1244 controls.
|
20506567 |
2011 |
|
rs533123
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We confirmed that common single-nucleotide polymorphisms (SNPs) within OPRD1 (rs533123, P=0.0015) confer risk for AN, and obtained suggestive evidence that common SNPs near HTR1D (rs7532266, P=0.04) confer risk for restricting-type AN specifically.
|
21079607 |
2011 |
|
rs7532266
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We confirmed that common single-nucleotide polymorphisms (SNPs) within OPRD1 (rs533123, P=0.0015) confer risk for AN, and obtained suggestive evidence that common SNPs near HTR1D (rs7532266, P=0.04) confer risk for restricting-type AN specifically.
|
21079607 |
2011 |
|
rs1049353
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Present findings show for the first time that the CNR1 1359 G/A SNP and the FAAH cDNA 385C to A SNP are significantly associated to anorexia nervosa and bulimia nervosa, and demonstrate a synergistic effect of the two SNPs in anorexia nervosa.
|
19659925 |
2009 |