Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17235409
rs17235409
0.030 GeneticVariation BEFREE In heterozygous comparison, it no association was shown between R</span>A and NRAMP1 D543N and INT4, excepting NRAMP1 1729 + 55del4 (OR 1.73, 95% CI 1.17-2.56). 30345642

2018

dbSNP: rs17235409
rs17235409
0.030 GeneticVariation BEFREE We found a significant association between INT4 and RA (P = 0.004, odds ratio: 2.06, 95% CI: 1.24-3.41), but no significant differences between 5' promoter, D543N, 3'UTR polymorphisms and RA. 19055603

2009

dbSNP: rs17235409
rs17235409
0.030 GeneticVariation BEFREE Three NRAMP1 polymorphisms (823C/T, D543N and 1729+55del4) were significantly associated with RA. 10719815

2000

dbSNP: rs3731865
rs3731865
0.020 GeneticVariation BEFREE Significant associations were observed between the 469+14G/C polymorphism (rs3731865) and autoimmune disease (OR=1.30 (1.04-1.64)) and rheumatoid arthritis (OR=1.60 (1.20-2.13)) and between the -237C/T polymorphism (rs7573065) and inflammatory bowel disease (OR=0.60 (0.43-0.84)). 25856512

2015

dbSNP: rs3731865
rs3731865
0.020 GeneticVariation BEFREE We analysed four NRAMP1 gene polymorphisms including 5' promoter (GT)(n) (rs34448891), INT4 (469 + 14G/C) (rs3731865), 3'UTR (1729 + 55del4) (rs17235416) and D543N (codon 543, Asp to Asn) (rs17235409) in 112 patients with TB, 98 patients with RA, 80 healthy controls for TB and 122 healthy controls for RA using ARMS-PCR and PCR-RFLP. 19055603

2009

dbSNP: rs17221959
rs17221959
0.010 GeneticVariation BEFREE CONCLUSIONS This study suggested that the TT genotype and T allele in rs17221959 decreased RA risk. 31316048

2019

dbSNP: rs7573065
rs7573065
0.010 GeneticVariation BEFREE Significant associations were observed between the 469+14G/C polymorphism (rs3731865) and autoimmune disease (OR=1.30 (1.04-1.64)) and rheumatoid arthritis (OR=1.60 (1.20-2.13)) and between the -237C/T polymorphism (rs7573065) and inflammatory bowel disease (OR=0.60 (0.43-0.84)). 25856512

2015

dbSNP: rs17235416
rs17235416
0.010 GeneticVariation BEFREE We analysed four NRAMP1 gene polymorphisms including 5' promoter (GT)(n) (rs34448891), INT4 (469 + 14G/C) (rs3731865), 3'UTR (1729 + 55del4) (rs17235416) and D543N (codon 543, Asp to Asn) (rs17235409) in 112 patients with TB, 98 patients with RA, 80 healthy controls for TB and 122 healthy controls for RA using ARMS-PCR and PCR-RFLP. 19055603

2009

dbSNP: rs34448891
rs34448891
0.010 GeneticVariation BEFREE We analysed four NRAMP1 gene polymorphisms including 5' promoter (GT)(n) (rs34448891), INT4 (469 + 14G/C) (rs3731865), 3'UTR (1729 + 55del4) (rs17235416) and D543N (codon 543, Asp to Asn) (rs17235409) in 112 patients with TB, 98 patients with RA, 80 healthy controls for TB and 122 healthy controls for RA using ARMS-PCR and PCR-RFLP. 19055603

2009