|
rs1222213359
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The present study is the first to document an association between VEGFA -1154G/A and reduced risk in women with RA but not with SLE.
|
29756413 |
2018 |
|
rs1222213359
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The -1154 A/G VEGF gene polymorphism under the codominant, recessive (AA+AG vs. GG) and dominant (AA vs. AG+GG) models were associated with RA (p = 0.0009; p = 0.004; p = 0.017, respectively).
|
27513931 |
2016 |
|
rs2010963
|
|
|
0.040 |
GeneticVariation |
BEFREE |
VEGFA rs699947 C/A, rs2010963 G/C, and rs3025039 C/T polymorphisms were not associated with the risk of RA.
|
23848209 |
2013 |
|
rs1222213359
|
|
|
0.040 |
GeneticVariation |
BEFREE |
To determine the contribution of the vascular endothelial growth factor A (VEGFA) rs2010963 (-634 G>C) and rs1570360 (-1154 G>A) polymorphisms to the risk of cardiovascular (CV) disease in a series of patients with rheumatoid arthritis (RA).
|
21388351 |
2011 |
|
rs2010963
|
|
|
0.040 |
GeneticVariation |
BEFREE |
No significant association between the VEGFA rs2010963 and the rs1570360 polymorphisms (neither isolated nor joined as allelic combinations) with clinically evident CV disease was found in this series of patients with RA.
|
21388351 |
2011 |
|
rs2010963
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Our data suggested a trend of association between VEGF gene polymorphisms and RA, and patients who carried the haplotype GA of rs2010963 and rs833070 were more susceptible to RA.
|
21245770 |
2011 |
|
rs1222213359
|
|
|
0.040 |
GeneticVariation |
BEFREE |
No evidence of association was observed between the -1154 G-->A and the -634 G-->C VEGF polymorphisms, or inferred VEGF haplotypes with RA susceptibility or clinical manifestations.
|
16216669 |
2005 |
|
rs2010963
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The aim of this study was to asses the role of -1154 G-->A (rs1570360) and -634 G-->C (rs2010963) VEGF gene functional variants with rheumatoid arthritis (RA).
|
16216669 |
2005 |
|
rs3025039
|
|
|
0.030 |
GeneticVariation |
BEFREE |
VEGFA rs699947 C/A, rs2010963 G/C, and rs3025039 C/T polymorphisms were not associated with the risk of RA.
|
23848209 |
2013 |
|
rs3025039
|
|
|
0.030 |
GeneticVariation |
BEFREE |
PCR-RFLP assays were used to determine the genotypes of VEGFA single-nucleotide polymorphisms (SNP) including VEGFA-2578A/C (rs699947), -460C/T (rs833061), +405C/G (rs2010963), and +936C/T (rs3025039) in 418 subjects with RA.
|
21362767 |
2011 |
|
rs3025039
|
|
|
0.030 |
GeneticVariation |
BEFREE |
There were increased genotype frequencies in GA of rs833070, GC of rs3025030, CT of rs3025039 and decreased genotype frequencies in GG of rs833070, GG of rs3025030, CC of rs3025039 in the patients with RA compared with the controls.
|
21245770 |
2011 |
|
rs833070
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Statistically significant difference was observed in DAS28 between the different genotypes of VEGF rs833070 in RA patients (P<0.05).
|
26825024 |
2016 |
|
rs699947
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These findings suggest that the functional single nucleotide polymorphism (SNP) VEGFA rs699947 C/A allele may decrease the risk of RA in older patients and ACPA-negative patients.
|
23848209 |
2013 |
|
rs1570360
|
|
|
0.020 |
GeneticVariation |
BEFREE |
No significant association between the VEGFA rs2010963 and the rs1570360 polymorphisms (neither isolated nor joined as allelic combinations) with clinically evident CV disease was found in this series of patients with RA.
|
21388351 |
2011 |
|
rs699947
|
|
|
0.020 |
GeneticVariation |
BEFREE |
PCR-RFLP assays were used to determine the genotypes of VEGFA single-nucleotide polymorphisms (SNP) including VEGFA-2578A/C (rs699947), -460C/T (rs833061), +405C/G (rs2010963), and +936C/T (rs3025039) in 418 subjects with RA.
|
21362767 |
2011 |
|
rs833070
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our data suggested a trend of association between VEGF gene polymorphisms and RA, and patients who carried the haplotype GA of rs2010963 and rs833070 were more susceptible to RA.
|
21245770 |
2011 |
|
rs1570360
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this study was to asses the role of -1154 G-->A (rs1570360) and -634 G-->C (rs2010963) VEGF gene functional variants with rheumatoid arthritis (RA).
|
16216669 |
2005 |
|
rs3025030
|
|
|
0.010 |
GeneticVariation |
BEFREE |
VEGF rs833070 and rs3025030 polymorphisms were associated with increasing VEGF serum levels in the RA group (all P<0.01).
|
26825024 |
2016 |