|
rs104894228
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs104894229
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs104894230
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs104894230
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1048943
|
|
|
0.020 |
GeneticVariation |
BEFREE |
CYP1A1 (Ile462Val), CYP1B1 (Ala119Ser and Val432Leu), GSTM1 (null), and GSTT1 (null) polymorphisms and bladder cancer risk in a Turkish population.
|
23886208 |
2013 |
|
rs1048943
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate a possible association of the CYP1A1 Ile462Val and GSTM1 null polymorphisms with the risk of developing bladder cancer in a Turkish population.
|
21709011 |
2011 |
|
rs104894360
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1050450
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present meta-analysis provides evidence that the GPX1 rs1050450 C > T polymorphism leads to an increased risk of BC but not the risk of PCa.
|
23975365 |
2014 |
|
rs10511729
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ASSET analyses identified four SNPs significantly associated with multiple cancers: rs3731239 (CDKN2A intronic) with ESCC, GC and BC (P = 3.96 × 10(-) (4)); rs10811474 (3' of IFNW1) with RCC and BrC (P = 0.001); rs12683422 (LINGO2 intronic) with RCC and BC (P = 5.93 × 10(-) (4)) and rs10511729 (3' of ELAVL2) with LC and BrC (P = 8.63 × 10(-) (4)).
|
25239644 |
2014 |
|
rs1051730
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we investigated the roles of variations at 5p15 (rs401681, rs402710, rs2736098 and rs2736100) and 15q25 (rs1051730 and rs8034191) in bladder cancer etiology in two case-control studies conducted separately in Los Angeles County, CA, USA (498 cases and 588 controls) and in Shanghai, China (506 cases and 530 controls).
|
21081471 |
2011 |
|
rs1051740
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer.
|
21445251 |
2011 |
|
rs1052133
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In conclusion, our results suggest that hOGG1 Ser326Cys polymorphism may contribute to the susceptibility to bladder cancer in a Chinese population.
|
22463382 |
2012 |
|
rs1052133
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Overall, no significant association between the hOGG1 Ser326Cys polymorphism and bladder cancer</span> risk was found for Cys/Cys vs Ser/Ser (OR = 1.10, 95%CI = 0.74-1.65), Ser/Cys vs Ser/Ser (OR = 1.07, 95%CI = 0.81-1.42), Cys/Cys + Ser/Cys vs Ser/Ser (OR = 1.08, 95%CI = 0.87-1.33), and Cys/Cys vs Ser/Cys + Ser/Ser (OR = 1.04, 95%CI = 0.65-1.69).
|
23079842 |
2012 |
|
rs1052133
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Consistent with the above findings, we found that the ADPRT V762A was only significantly involved in bladder cancer</span> risk in never smokers and the OGG1 S326C was only significantly involved in ever smokers.
|
17220334 |
2007 |
|
rs1052133
|
|
|
0.070 |
GeneticVariation |
BEFREE |
We undertook a case-control study of 212 urothelial bladder cancer (UBC) cases and 250 controls to investigate the association between OGG1 (C1245G rs1052133), XRCC3 (C18067T, rs861539) and XRCC7 (G6721T, rs7003908) polymorphisms and bladder cancer susceptibility by PCR-RFLP and the ARMS method.
|
19815090 |
2010 |
|
rs1052133
|
|
|
0.070 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that the hOGG1 Ser326Cys polymorphism may be a risk factor for bladder cancer without exposure to smoking.
|
22857644 |
2012 |
|
rs1052133
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Among four DNA repair gene polymorphisms, the OGG1 326 Ser/Cys and XPD 312 Asp/Asn heterozygous genotypes might be recognized as potential genetic markers modifying susceptibility to bladder cancer in Belarus.
|
25089939 |
2014 |
|
rs1052133
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The overall current literature on hOGG1 Ser326Cys polymorphism and the risk of bladder cancer suggests no statistically significant association between the two.
|
22156293 |
2012 |
|
rs1056827
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CYP1A1 (Ile462Val), CYP1B1 (Ala119Ser and Val432Leu), GSTM1 (null), and GSTT1 (null) polymorphisms and bladder cancer risk in a Turkish population.
|
23886208 |
2013 |
|
rs1056836
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, based on 17 eligible studies, we found that the CYP1B1 Leu432Val polymorphism was associated with an increased risk of prostate cancer, while no association of bladder cancer was observed.
|
24453031 |
2014 |
|
rs1056836
|
|
|
0.020 |
GeneticVariation |
BEFREE |
CYP1A1 (Ile462Val), CYP1B1 (Ala119Ser and Val432Leu), GSTM1 (null), and GSTT1 (null) polymorphisms and bladder cancer risk in a Turkish population.
|
23886208 |
2013 |
|
rs1057519958
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis from TCGA raised the possibility that hyperactive PPAR signaling, either due to PPAR gamma gene amplification or RXRA hot-spot mutation (S427F/Y) drives 20-25% of human bladder cancers.
|
29143738 |
2017 |
|
rs1057868
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, we first sequenced all 16 POR exons among 50 randomly selected controls, and found three variants, rs1135612, rs1057868 (A503V) and rs2228104, which were then assessed the relation to risk of bladder cancer in a case-control study of 1,050 bladder cancer cases and 1,404 cancer-free controls in a Chinese population.
|
26123203 |
2015 |
|
rs1063054
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, positive associations were found for rs709816 with bladder cancer (OR(adj) = 4.2, 95% CI: 1.4, 12) and rs1063054 with lung cancer (OR(adj) = 1.6, 95% CI: 1.0, 2.3).
|
20478923 |
2010 |
|
rs1063192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified that rs1063192 and rs2157719 in the CDKN2A/2B region were significantly associated with ESCC and rs2764736 (3' of TUSC1) was associated with BC (P ≤ 2.59 × 10(-6)).
|
25239644 |
2014 |