|
rs1801394
|
|
|
0.070 |
GeneticVariation |
BEFREE |
SHMT C1420T mutations may reduce breast cancer susceptibility, whereas MTRR A66G and MS A2756G mutations may increase breast cancer susceptibility.
|
27347936 |
2016 |
|
rs1801394
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Cross-talk was observed between one-carbon and xenobiotic pathways in breast cancer (RFC 80 G>A, COMT H108L and TYMS 5'-UTR 28 bp tandem repeat) and SLE (CYP1A1 m1, MTRR 66 A>G and GSTT1).
|
25648260 |
2015 |
|
rs1801394
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Our findings suggested that MTRR A66G polymorphism was not associated with breast cancer susceptibility.
|
24815481 |
2014 |
|
rs1801394
|
|
|
0.070 |
GeneticVariation |
BEFREE |
MTRR A66G and cSHMT C1420T polymorphisms influence CIMP phenotype of BNIP3, thus epigenetically regulating BNIP3 in breast cancer.
|
21987236 |
2012 |
|
rs1801394
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis strongly suggests that MTRR A66G polymorphism is not associated with breast cancer risk, especially in Caucasians and Asians.
|
20411324 |
2010 |
|
rs1801394
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In addition, interaction between the MTRR A66G polymorphism and folate intake for risk of postmenopausal breast cancer was observed (interaction P = 0.008).
|
18174236 |
2008 |
|
rs1801394
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Viable cell growth, MDI, and polymorphism frequency in MTRR (A66G and C524T) and MTHFR (A1298C and A1793G) did not differ among the study groups; however, MDI tended to be higher in BRCA carriers with breast cancer than those without and was significantly increased in MTHFR 677T allele carriers relative to wild-type carriers (P=0.017).
|
18842997 |
2008 |
|
rs10380
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found three single-nucleotide polymorphisms in those genes associated with LINE-1 methylation: SLC19A1 (rs1051266); MTRR (rs10380) and MTHFR (rs1537514), one of which was also associated with breast cancer risk: MTHFR (rs1537514).
|
24130171 |
2014 |
|
rs162049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A stratified analysis by menopausal status indicated the association between the NAT2 SNP (rs1799930) and breast cancer was mainly evident in premenopausal women (OR 2.70, 95% CI 1.20-6.07), while the MTRR SNP (rs162049) was significant in postmenopausal women (OR 1.61, 95% CI 1.07-2.44).
|
20180013 |
2010 |
|
rs1532268
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Viable cell growth, MDI, and polymorphism frequency in MTRR (A66G and C524T) and MTHFR (A1298C and A1793G) did not differ among the study groups; however, MDI tended to be higher in BRCA carriers with breast cancer than those without and was significantly increased in MTHFR 677T allele carriers relative to wild-type carriers (P=0.017).
|
18842997 |
2008 |
|
rs752681512
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Viable cell growth, MDI, and polymorphism frequency in MTRR (A66G and C524T) and MTHFR (A1298C and A1793G) did not differ among the study groups; however, MDI tended to be higher in BRCA carriers with breast cancer than those without and was significantly increased in MTHFR 677T allele carriers relative to wild-type carriers (P=0.017).
|
18842997 |
2008 |