|
rs2228570
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The TCTCTG-rs9533156-rs2073618-rs2073617-rs4950928-rs2228570-rs1544410 haplotype was significantly associated with increased BC risk (adjusted odds ratio = 8.33; 95% confidence interval, 1.32-52.46; P = .025) compared with controls.
|
30309792 |
2019 |
|
rs2228570
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The rs2228570 <i>GG</i> genotype was associated with increased risk of breast cancer (OR = 1.44, 95% confidence interval = 1.01-2.06).
|
30699973 |
2019 |
|
rs2228570
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association of FokI (rs2228570) and BsmI (rs1544410) single nucleotide polymorphisms (SNPs) in VDR gene with the risk of breast cancer have been investigated in several studies, however, the published data are still inconsistent.
|
28780723 |
2018 |
|
rs2228570
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The recessive polymorphism model with the rs2228570 (FokI) polymorphism seemed to the best predictor of BC in Caucasian patients, whereas the homozygote model with the CDX2 polymorphism appeared to best predict BC in African-American patients.
|
30059751 |
2018 |
|
rs2228570
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two common single nucleotide polymorphisms (SNPs) in the VDR gene, rs1544410 (BsmI) and rs2228570 (FokI), are inconsistently associated with breast cancer risk in Caucasian populations, while data for Asians are scarce.
|
26517870 |
2015 |
|
rs2228570
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Sunlight measures were not associated with breast cancer risk, however significant interactions between time outdoors in the teen years and three unlinked genotypes were found for VDR (rs1544410, rs2228570) and CYP24A1 (rs1570669).
|
23393347 |
2013 |
|
rs2228570
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We assessed the association of genetic variants in VDR (rs731236, rs1989969, rs2228570, and 11568820) with breast cancer survival in a sample of 498 patients with breast cancer with a mean age at diagnosis of 61 years from Saarland, Germany, who were followed for up to 5 years with respect to total and breast cancer-specific mortality (56 and 48 events, respectively).
|
23300018 |
2013 |
|
rs2228570
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The most extensively studied SNPs including rs10735810, also known as rs2228570 (Fok1, VDR), rs1544410 (Bsm1, VDR), and rs2296241 (CYP24A1), were not associated with breast cancer risk.
|
21828234 |
2011 |
|
rs2228570
|
|
|
0.100 |
GeneticVariation |
BEFREE |
For example, breast cancer risk was associated with the GC rs7041 TT genotype (age-adjusted odds ratio (OR) = 1.23; 95% CI: 1.01, 1.51) and inversely with the VDR Fok1 (rs2228570) ff genotype (OR = 0.71; 95% CI: 0.57, 0.88).
|
21693626 |
2011 |
|
rs2228570
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two common single nucleotide polymorphisms (SNP) in the VDR gene (VDR), rs1544410 (BsmI), and rs2228570 (FokI), have been inconsistently associated with breast cancer risk.
|
19124512 |
2009 |
|
rs1544410
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The TCTCTG-rs9533156-rs2073618-rs2073617-rs4950928-rs2228570-rs1544410 haplotype was significantly associated with increased BC </span>risk (adjusted odds ratio = 8.33; 95% confidence interval, 1.32-52.46; P = .025) compared with controls.
|
30309792 |
2019 |
|
rs1544410
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Association of FokI (rs2228570) and BsmI (rs1544410) single nucleotide polymorphisms (SNPs) in VDR gene with the risk of breast cancer have been investigated in several studies, however, the published data are still inconsistent.
|
28780723 |
2018 |
|
rs1544410
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Two common single nucleotide polymorphisms (SNPs) in the VDR gene, rs1544410 (BsmI) and rs2228570 (FokI), are inconsistently associated with breast cancer risk in Caucasian populations, while data for Asians are scarce.
|
26517870 |
2015 |
|
rs1544410
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The role of the rs1544410 polymorphism of vitamin D receptor gene in breast cancer susceptibility.
|
25064221 |
2014 |
|
rs1544410
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Sunlight measures were not associated with breast cancer risk, however significant interactions between time outdoors in the teen years and three unlinked genotypes were found for VDR (rs1544410, rs2228570) and CYP24A1 (rs1570669).
|
23393347 |
2013 |
|
rs1544410
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The most extensively studied SNPs including rs10735810, also known as rs2228570 (Fok1, VDR), rs1544410 (Bsm1, VDR), and rs2296241 (CYP24A1), were not associated with breast cancer risk.
|
21828234 |
2011 |
|
rs1544410
|
|
|
0.070 |
GeneticVariation |
BEFREE |
No association was noted between rs1544410 (BsmI) BB and breast cancer risk overall (OR, 0.98; 95% CI, 0.89-1.09), but the BB genotype was associated with a significantly lower risk of advanced breast cancer (OR, 0.74; 95% CI, 0.60-0.92).
|
19124512 |
2009 |
|
rs731236
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The aim of this study was to determine whether C to T base substitution within TaqI Vitamin D receptor (VDR) gene (rs731236) in exon 9 was a risk factor among patients with breast cancer.
|
28469103 |
2017 |
|
rs731236
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The authors found that TC in rs731236, and TG in KY859868 single-nucleotide polymorphism showed significant distribution differences with an increased risk of breast cancer ( p < 0.05, odds ratio = 3.71, 95% confidence interval: 1.04-13.28 and p < 0.001, odds ratio = 7.05, 95% confidence interval: 2.02-24, respectively) compared with the wild-type TT genotype carriers in both single-nucleotide polymorphisms.
|
29022486 |
2017 |
|
rs731236
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Our analysis suggests that VDR polymorphism rs731236 might be associated with breast cancer-specific mortality, and if our findings are confirmed in future bigger studies rs731236 might deserve consideration as a prognostic factor in clinical care of patients with breast cancer.
|
23300018 |
2013 |
|
rs731236
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The aim of the study was to determine whether four VDR gene single nucleotide polymorphisms (SNPs: rs1544410, rs731236, rs10735810 and rs4516035) are associated with breast cancer risk in Polish population.
|
18587672 |
2009 |
|
rs10735810
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The most extensively studied SNPs including rs10735810, also known as rs2228570 (Fok1, VDR), rs1544410 (Bsm1, VDR), and rs2296241 (CYP24A1), were not associated with breast cancer risk.
|
21828234 |
2011 |
|
rs10735810
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Examination of the group of early-onset patients, revealed an association between rs10735810 and increased breast cancer risk.
|
18587672 |
2009 |
|
rs1989969
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We assessed the association of genetic variants in VDR (rs731236, rs1989969, rs2228570, and 11568820) with breast cancer survival in a sample of 498 patients with breast cancer with a mean age at diagnosis of 61 years from Saarland, Germany, who were followed for up to 5 years with respect to total and breast cancer-specific mortality (56 and 48 events, respectively).
|
23300018 |
2013 |
|
rs11168287
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In individual SNP analyses, homozygous carriers of the minor allele for rs2544038 had significantly increased breast cancer risk (OR = 1.5; 95% CI: 1.0-2.5) and homozygous carriers of the minor allele for rs11168287 had significantly decreased risk (OR = 0.6; 95% CI: 0.4-1.0).
|
22892281 |
2012 |